CAS 2623-33-8

p-Acetoxyacetanilide

Description:

p-Acetoxyacetanilide, also known as paracetamol acetate, is an organic compound characterized by its acetyl and acetamide functional groups. It is a white to off-white crystalline solid that is soluble in organic solvents but has limited solubility in water. The compound is primarily used in pharmaceutical applications, often as an intermediate in the synthesis of analgesics and antipyretics. Its structure features an acetoxy group attached to the para position of an acetanilide moiety, which contributes to its biological activity. p-Acetoxyacetanilide exhibits properties similar to those of paracetamol, including pain-relieving and fever-reducing effects, although its specific pharmacological profile may differ. The compound should be handled with care, as it may pose health risks if ingested or inhaled, and appropriate safety measures should be observed during its use in laboratory or industrial settings. Overall, p-Acetoxyacetanilide represents an important compound in medicinal chemistry, with potential applications in drug development and synthesis.

Formula: C₁₀H₁₁NO₃

InChI: InChI=1/C10H11NO3/c1-7(12)11-9-3-5-10(6-4-9)14-8(2)13/h3-6H,1-2H3,(H,11,12)

InChI key: InChIKey=UJAOSPFULOFZRR-UHFFFAOYSA-N

SMILES: N(C(C)=O)C1=CC=C(OC(C)=O)C=C1

Synonyms:

• 4-(Acetylamino)Phenyl Acetate
• 4-Acetamidophenyl Acetate
• 4-Acetylaminophenyl acetate
• 4′-Acetoxyacetanilide
• Acetamide, N-[4-(acetyloxy)phenyl]-
• Acetaminophen acetate
• Acetanilide, 4′-hydroxy-, acetate
• Acetanilide, 4′-hydroxy-, acetate (ester)
• Diacetylaminophenol
• N-(4-Acetoxyphenyl)acetamide
• N-Acetyl-4-aminophenyl acetate
• N-[4-(Acetyloxy)phenyl]acetamide
• NSC 33893
• NSC 6083
• O,N-Diacetyl-4-aminophenol
• O-Acetylparacetamol
• p-Acetamidophenyl acetate
• p-Acetoxyacetanilide
• Acetaminophen Impurity
• Diacetamate
• n-[4-(acetyloxy)phenyl]-acetamid
• Diacetamat
• ACETAMINOPHEN IMPURITY H
• 4'-Hydroxyacetanilide Acetate
• Acetaminophen Acetate (Acetaminophen Impurity)
• N,O-DIACETYL-4-AMINOPHENOL

4'-Acetoxyacetanilide

CAS: 2623-33-8

Formula: C₁₀H₁₁NO₃

Purity: >99.0%(HPLC)(N)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 193.20

Ref: 3B-A0067

Acetaminophen Related Compound A (4-(acetylamino)phenyl acetate)

CAS: 2623-33-8

Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereof

Formula: C₁₀H₁₁NO₃

Color and Shape: White Powder

Molecular weight: 193.07389

Ref: 45-1003010

N,O-Diacetyl-4-aminophenol

CAS: 2623-33-8

Formula: C₁₀H₁₁NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 193.1992

Ref: IN-DA002SDM

Paracetamol (Acetaminophen) EP Impurity H

CAS: 2623-33-8

Formula: C₁₀H₁₁NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 193.20

Ref: 4Z-A-027

p-Acetoxyacetanilide

CAS: 2623-33-8

p-Acetoxyacetanilide

Purity: 98%

Molecular weight: 193.20g/mol

Ref: 54-OR914021

4-(Acetylamino)phenyl Acetate (N,O-Diacetyl-4-aminophenol)

Controlled Product

CAS: 2623-33-8

Formula: C₁₀H₁₁NO₃

Color and Shape: Neat

Molecular weight: 193.20

Ref: 86-MM0042.04

4-Acetamidophenyl acetate

CAS: 2623-33-8

4-Acetamidophenyl acetate is an acetaminophen impurity, COX-2 inhibitor (IC50: 25.8 μM), and strong NAT2 inhibitor.

Formula: C₁₀H₁₁NO₃

Color and Shape: White Solid

Molecular weight: 193.2

Ref: TM-T10135

Paracetamol EP Impurity H

CAS: 2623-33-8

Formula: C₁₀H₁₁NO₂

Molecular weight: 193.20

Ref: ST-EA-CP-P10008

Acetaminophen Acetate (Acetaminophen Impurity)

CAS: 2623-33-8

Impurity Paracetamol EP Impurity H/ Acetaminophen impurity H
Applications Acetaminophen Acetate is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).
References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)

Formula: C₁₀H₁₁NO₃

Color and Shape: White To Off-White

Molecular weight: 193.20

Ref: TR-A161215

Acetaminophen acetate

CAS: 2623-33-8

Acetaminophen acetate is a cholinergic amine that binds to the active site of the enzyme acetylcholine esterase, preventing it from breaking down acetylcholine. Acetaminophen is used as a pain reliever and antipyretic agent. It is also used for its anti-inflammatory effects in the treatment of rheumatoid arthritis and other inflammatory conditions. Acetaminophen has been shown to have anticancer properties, which may be due to its ability to bind to cancer cells, inhibit their growth, and induce apoptosis. Acetaminophen acetate is also an acylation reaction product that can be isolated by liquid chromatography in phase with fluorescence properties.

Formula: C₁₀H₁₁NO₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 193.2 g/mol

Ref: 3D-IA16944

4-Acetamidophenyl acetate

CAS: 2623-33-8

Formula: C₁₀H₁₁NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 193.202

Ref: 10-F544578

Acetaminophen EP Impurity H

CAS: 2623-33-8

Formula: C₁₀H₁₁NO₃

Molecular weight: 193.2

Ref: ST-EA-CP-A7033

4-(Acetylamino)phenyl Acetate (N,O-Diacetyl-4-aminophenol)

CAS: 2623-33-8

Color and Shape: Neat

Ref: 61-FOR0042.04