CAS 2627-69-2
:AICAr
Description:
AICAr, or 5-aminoimidazole-4-carboxamide ribonucleotide, is a chemical compound that plays a significant role in cellular metabolism, particularly in the purine biosynthesis pathway. It is a nucleotide precursor that is involved in the synthesis of adenosine monophosphate (AMP). AICAr is known for its potential effects on cellular energy metabolism and has been studied for its role in activating AMP-activated protein kinase (AMPK), which is crucial for regulating energy homeostasis. The compound is often investigated in the context of metabolic disorders, exercise physiology, and potential therapeutic applications for conditions such as obesity and type 2 diabetes. AICAr is typically characterized by its molecular structure, which includes an imidazole ring and a ribonucleotide component. Its CAS number, 2627-69-2, is a unique identifier that facilitates the identification and study of this compound in scientific literature and databases. Overall, AICAr is a significant molecule in biochemistry with implications for health and disease management.
Formula:C9H14N4O5
InChI:InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1
InChI key:InChIKey=RTRQQBHATOEIAF-UUOKFMHZSA-N
SMILES:O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(N)=C(C(N)=O)N=C2
Synonyms:- 1-Ribosyl-4-carboxamido-5-aminoimidazole
- 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-5-amino-4-imidazolecarboxamide
- 1H-Imidazole-4-carboxamide, 5-amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- 5-Amino-1-beta-ribofuranosyl-imidazole-4-carboxamide
- 5-Amino-1-ribosyl-4-imidazolecarboxamide
- 5-Amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-imidazole-4-carboxamide
- 5-Amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosylimidazole-4-carboxamide
- 5-Amino-1beta-D-ribofuranosylimidazole-4-carboxamide
- 5-Amino-4-imidazolecarboxamide ribofuranoside
- 5-Amino-4-imidazolecarboxamide riboside
- 5-Aminoimidazole-4-carboxamid-1-β-<span class="text-smallcaps">D</span>-ribofuranoside
- 5-Aminoimidazole-4-carboxamide 1-(β-<span class="text-smallcaps">D</span>-ribofuranoside)
- 5-Aminoimidazole-4-carboxamide ribonucleoside
- 5-Aminoimidazole-4-carboxamide riboside
- 5-Aminoimidazole-4-carboxamide-1-§-D-Ribofuranoside
- 5-amino-1-(beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide
- AIC-Riboside
- AICA-riboside
- Acadra
- Aicar
- Arasine
- Gp 1-110
- Imidazole-4-carboxamide, 5-amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- NSC 105823
- 5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide
- 1H-Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 11 products.
5-Aminoimidazole-4-carboxamide 1-β-D-Ribofuranoside
CAS:Formula:C9H14N4O5Purity:>98.0%(HPLC)Color and Shape:White to Light yellow to Light red powder to crystalMolecular weight:258.235-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside, 98%
CAS:<p>Activator of AMP-activated protein kinase (AMPK)</p>Formula:C9H14N4O5Purity:98%Molecular weight:258.23AICAR
CAS:<p>AICAR (Acadesine) is an AMPK activator, metabolic regulation, muscle function regulation, anti-cancer effect, neuroprotection. High-Quality, Low-Cost!</p>Formula:C9H14N4O5Purity:98.00% - ≥95%Color and Shape:SolidMolecular weight:258.235-Amino-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxamide
CAS:<p>5-Amino-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxamide</p>Formula:C9H14N4O5Purity:97%Color and Shape: off-white to white solidMolecular weight:258.23g/molAcadesine
CAS:Formula:C9H14N4O5Purity:≥ 98.0%Color and Shape:White to beige solidMolecular weight:258.235-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside
CAS:<p>Applications AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.<br>References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)<br></p>Formula:C9H14N4O5Color and Shape:NeatMolecular weight:258.235-Aminoimidazole-4-carboxamide-1-b-D-ribofuranose
CAS:<p>Acadesine is a purine nucleoside analogue that inhibits the synthesis of ATP in cells. Acadesine blocks phosphorylation of adenosine monophosphate (AMP) to adenosine triphosphate (ATP) by inhibiting the activity of kinase-3, an enzyme involved in the production of ATP. Acadesine also inhibits the release of ATP from muscle cells into the blood stream and preferentially targets kidney cells, thereby reducing renal injury. Acadesine has been shown to be effective at reducing proteinuria and improving renal function in rats with acute kidney injury. Acadesine also has anti-inflammatory properties due to its ability to inhibit proteins that are involved in inflammation.</p>Formula:C9H14N4O5Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:258.23 g/molAICA Riboside
CAS:<p>M04018 - AICA Riboside</p>Formula:C9H14N4O5Purity:98%Color and Shape:SolidMolecular weight:258.2345-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside-15N4
CAS:Controlled Product<p>Applications A labelled nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.<br>References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)<br></p>Formula:C9H1415N4O5Color and Shape:NeatMolecular weight:262.205-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide
CAS:Formula:C9H14N4O5Purity:95%Color and Shape:SolidMolecular weight:258.2313
