CAS 26287-72-9

L-Ribofuranose, 1-acetate 2,3,5-tribenzoate

Description:

L-Ribofuranose, 1-acetate 2,3,5-tribenzoate is a chemical compound that belongs to the class of ribonucleosides, specifically a derivative of ribofuranose. This compound features a ribofuranose sugar moiety that is acetylated at the 1-position and has three benzoate groups esterified at the 2, 3, and 5 positions. The presence of these benzoate groups contributes to its hydrophobic characteristics, which can influence its solubility and reactivity. The acetyl group enhances the stability of the molecule and can affect its biological activity. This compound is often used in biochemical research and synthetic organic chemistry, particularly in studies related to nucleic acids and their derivatives. Its structure allows for potential interactions with various biological targets, making it of interest in medicinal chemistry. As with many derivatives of sugars, it may exhibit specific stereochemical properties that are crucial for its function and interactions in biological systems.

Formula: C₂₈H₂₄O₉

InChI: InChI=1S/C28H24O9/c1-18(29)34-28-24(37-27(32)21-15-9-4-10-16-21)23(36-26(31)20-13-7-3-8-14-20)22(35-28)17-33-25(30)19-11-5-2-6-12-19/h2-16,22-24,28H,17H2,1H3/t22-,23-,24-,28?/m0/s1

InChI key: InChIKey=GCZABPLTDYVJMP-SXBSXPTQSA-N

SMILES: O(C(=O)C1=CC=CC=C1)[C@@H]2[C@H](OC(=O)C3=CC=CC=C3)C(OC(C)=O)O[C@H]2COC(=O)C4=CC=CC=C4

Synonyms:

• Ribofuranose, 1-acetate tribenzoate, L-
• 1-O-Acetyl-2,3,5-tri-O-benzoyl-L-ribose
• L-Ribofuranose, 1-acetate 2,3,5-tribenzoate

1-O-Acetyl-2,3,5-tri-O-benzoyl-L-ribose

Controlled Product

CAS: 26287-72-9

Applications 1-O-Acetyl-2,3,5-tri-O-benzoyl-L-ribose is an intermediate in the synthesis of L-Adenosine (A291823), an intermediate in the synthesis of (2S,3S,4R,5R)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol (A609900), an enantiomer of (2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol (A577286), which is an intermediate used in the synthesis of S-adenosylhomocysteine analogs with biological activities.
References Lawrence, F., et al.: Biochem. S-Adenosylmethionine Relat. Compd., Proc. Conf., 637 (1982); Shire, D., et al.: Nucleosides & Nucleotides, 2, 21 (1983)

Formula: C₂₈H₂₄O₉

Color and Shape: Neat

Molecular weight: 504.48

Ref: TR-A188645

1-o-Acetyl-2,3,5-tri-o-benzoyl-L-ribose

CAS: 26287-72-9

1-o-Acetyl-2,3,5-tri-o-benzoyl-L-ribose is a potent inhibitor of human kinases and has been shown to have anticancer properties. It is an analog of tumor suppressor protein and induces apoptosis in cancer cells. This compound has been found in the urine of Chinese medicinal plants and has been extensively studied for its potential use in cancer treatment. Its ability to inhibit kinases makes it a promising candidate for the development of new anticancer drugs. Additionally, 1-o-Acetyl-2,3,5-tri-o-benzoyl-L-ribose has been found to have significant anti-inflammatory effects, which may also make it useful in treating other diseases associated with inflammation. Overall, this compound shows great potential as a therapeutic agent for various diseases and conditions.

Formula: C₂₈H₂₄O₉

Purity: Min. 95%

Molecular weight: 504.5 g/mol

Ref: 3D-BBA28772