CAS 26296-54-8

9,10-Anthracenedione,1-(b-D-glucopyranosyloxy)-8-hydroxy-6-methoxy-3-methyl-

Description:

9,10-Anthracenedione, 1-(β-D-glucopyranosyloxy)-8-hydroxy-6-methoxy-3-methyl- is a complex organic compound characterized by its anthraquinone structure, which features a fused three-ring system. This compound contains various functional groups, including a glucopyranosyl moiety, hydroxyl groups, and methoxy groups, contributing to its solubility and reactivity. The presence of the β-D-glucopyranosyloxy group enhances its potential for biological activity, possibly influencing its interaction with biological systems. The hydroxyl and methoxy substituents can affect the compound's electronic properties, making it a candidate for applications in pharmaceuticals, dyes, or as a biochemical probe. Its CAS number, 26296-54-8, allows for precise identification in chemical databases. Overall, this compound's unique structure and functional groups suggest potential utility in various fields, including medicinal chemistry and materials science, although specific applications would depend on further research into its properties and behavior in different environments.

Formula: C₂₂H₂₂O₁₀

InChI: InChI=1S/C22H22O10/c1-8-3-10-16(19(27)15-11(17(10)25)5-9(30-2)6-12(15)24)13(4-8)31-22-21(29)20(28)18(26)14(7-23)32-22/h3-6,14,18,20-24,26,28-29H,7H2,1-2H3/t14-,18-,20+,21-,22-/m1/s1

InChI key: InChIKey=WLXGUTUUWXVZNM-DQMLXFRHSA-N

SMILES: O(C1=C2C(C(=O)C=3C(C2=O)=C(O)C=C(OC)C3)=CC(C)=C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O

Synonyms:

• 1-(β-<span class="text-smallcaps">D</span>-Glucopyranosyloxy)-8-hydroxy-6-methoxy-3-methyl-9,10-anthracenedione
• 3-Methyl-6-methoxy-1,8-dihydroxyanthraquinone 1-glucoside
• 9,10-Anthracenedione, 1-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-8-hydroxy-6-methoxy-3-methyl-
• Physcion 1-O-β-<span class="text-smallcaps">D</span>-glucopyranoside
• Physcion 1-O-β-<span class="text-smallcaps">D</span>-glucoside
• Physcion 1-b-D-glucopyranoside
• Physcion 1-β-<span class="text-smallcaps">D</span>-glucopyranoside
• Physcion1-O-b-D-glucoside
• Physcionin
• Physcionin(7CI,8CI)
• 9,10-Anthracenedione, 1-(β-D-glucopyranosyloxy)-8-hydroxy-6-methoxy-3-methyl-

9,10-Anthracenedione, 1-(β-D-glucopyranosyloxy)-8-hydroxy-6-methoxy-3-methyl-

CAS: 26296-54-8

Formula: C₂₂H₂₂O₁₀

Purity: 95%

Color and Shape: Solid

Molecular weight: 446.4041

Ref: IN-DA002SLO

Physcion 8-glucoside

CAS: 26296-54-8

Formula: C₂₂H₂₂O₁₀

Molecular weight: 446.41

Ref: 7W-GY7962

Physion 8-O-β-D-glucoside

CAS: 26296-54-8

Physion 8-O-β-D-glucoside

Purity: ≥95%

Molecular weight: 446.4g/mol

Ref: 54-BUP21357

Physcion 1-glucoside

CAS: 26296-54-8

Formula: C₂₂H₂₂O₁₀

Purity: 95%~99%

Molecular weight: 446.408

Ref: BP-BP4264

Physion 8-O-β-D-glucoside

CAS: 26296-54-8

Physion 8-O-β-D-glucoside is a tumor cell growth inhibitor.

Formula: C₂₂H₂₂O₁₀

Purity: 95.17% - 99.66%

Color and Shape: Solid

Molecular weight: 446.4

Ref: TM-TN1017

Physcion 1-b-D-Glucopyranoside

Controlled Product

CAS: 26296-54-8

Applications Physcion 1-β-D-Glucopyranoside is a by-product during the synthesis of Physcion 8-β-D-glucoside (P398100). Physcion 8-β-D-glucoside has been studied in research relating to the treatment of the glomerulonephritis. It is the glucoside of Physcion (P398000) which is a natural anthraquinone derivative, on the infection process of Blumeria graminis on wheat. Physcion is one of the important active ingredients of ethanol extract from the roots of Chinese rhubarb (Rheum officinale) for controlling powdery mildew.
References Kuo, Y.C. et al.: Life. Sci., 68, 1271 (2001); Thiericke, R., et al.: Nat. Prod. Rep.,10, 265 (1993); Lin, C., et al.: J. Nat. Prod., 58, 1934 (1995); Julia, S., et al.: J. Biotechnol., 124, 690 (2006); Wang, W., et al.: J. Antibiot., 60, 603 (2007);

Formula: C₂₂H₂₂O₁₀

Color and Shape: Neat

Molecular weight: 446.4

Ref: TR-P398103

Physcion-1-O-²-D-glucoside

CAS: 26296-54-8

Physcion-1-O-²-D-glucoside is a natural product that has been shown to have anti-cancer properties. It inhibits the growth of cancer cells by triggering apoptosis, or programmed cell death. Physcion-1-O-²-D-glucoside has also been shown to inhibit tumour growth in animal models and reduce the size of tumours in mice with implanted human xenografts. This compound is a potent inhibitor of paclitaxel resistance, which is an important factor in cancer chemotherapy. The mechanism of action for this compound has not yet been elucidated, but it has been suggested that it may interfere with the process of cell division through interference with microtubule formation or mitotic spindle function.

Formula: C₂₂H₂₂O₁₀

Purity: Min. 95%

Molecular weight: 446.41 g/mol

Ref: 3D-BBA29654