CAS 26328-04-1: Cinepazide maleate

Description: Cinepazide maleate is a pharmaceutical compound primarily used as a vasodilator and for its neuroprotective properties. It is classified as a derivative of the benzodiazepine family and is known for its ability to improve blood flow, particularly in the cerebral circulation. The maleate salt form enhances its solubility and stability, making it suitable for various formulations. Cinepazide maleate exhibits a mechanism of action that involves the modulation of neurotransmitter release and the inhibition of platelet aggregation, contributing to its therapeutic effects. The compound is typically administered in clinical settings for conditions related to impaired cerebral circulation, such as stroke or cognitive disorders. Its safety profile includes common side effects like dizziness or gastrointestinal disturbances, but it is generally well-tolerated. As with any medication, it is essential to consider contraindications and interactions with other drugs. Overall, Cinepazide maleate represents a valuable option in the management of vascular and neurological conditions.

Formula: C₂₂H₃₁N₃O₅·C₄H₄O₄

InChI: InChI=1S/C22H31N3O5.C4H4O4/c1-28-18-14-17(15-19(29-2)22(18)30-3)6-7-20(26)25-12-10-23(11-13-25)16-21(27)24-8-4-5-9-24;5-3(6)1-2-4(7)8/h6-7,14-15H,4-5,8-13,16H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key: InChIKey=XSTJTOKYCAJVMJ-BTJKTKAUSA-N

SMILES: O=C(O)C=CC(=O)O.O=C(C=CC=1C=C(OC)C(OC)=C(OC)C1)N2CCN(CC(=O)N3CCCC3)CC2

Synonyms:

• (E)-1-[4-(2-oxo-2-pyrrolidin-1-yl-ethyl)piperazin-1-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
• (Z)-but-2-enedioate
• 1-((1-Pyrrolidinylcarbonyl)methyl)-4-(3,4,5-trimethoxycinnamoyl)piperazine maleate
• 1-(2-Oxo-2-(1-pyrrolidinyl)ethyl)-4-(1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)piperazine (Z)-2-butenedioate (1:1)
• 1-(2-Oxo-2-pyrrolidin-1-ylethyl)-4-(3-(3,4,5-trimethoxyphenyl)acryloyl)piperazine monomaleate
• 1-(2-oxo-2-pyrrolidin-1-ylethyl)-4-[(2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]piperazine (2Z)-but-2-enedioate
• 1-(2-oxo-2-pyrrolidin-1-ylethyl)-4-[3-(3,4,5-trimethoxyphenyl)acryloyl]piperazine (2Z)-but-2-enedioate
• 1-(4-((3',4',5'-Trimethoxycinnamoyl)-1-piperazinyl)acetyl)pyrrolidine maleate
• 2-Propen-1-one, 1-[4-[2-oxo-2-(1-pyrrolidinyl)ethyl]-1-piperazinyl]-3-(3,4,5-trimethoxyphenyl)-, (2Z)-2-butenedioate (1:1)
• 4-(3,4,5-Trimethoxycinnamoyl)-1-(1-pyrrolidinyl)carbonylmethylpiperazine maleate
• Brendil
• Maleate de cinepazide
• Maleate de cinepazide [French]
• Md 67350
• Nsc 291562
• Piperazine, 1-((1-pyrrolidinylcarbonyl)methyl)-4-(3',4',5'-trimethoxycinnamoyl)-, maleate
• Piperazine, 1-(2-oxo-2-(1-pyrrolidinyl)ethyl)-4-(1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)-, (Z)-2-butenedioate (1:1) (9CI)
• Piperazine, 1-[(1-pyrrolidinylcarbonyl)methyl]-4-(3,4,5-trimethoxycinnamoyl)-, maleate (1:1)
• Piperazine, 1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-4-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-, (2Z)-2-butenedioate (1:1)
• Piperazine, 1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-4-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-, (Z)-2-butenedioate (1:1)
• Vasodistal
• Cinepazide maleate

Cinepazide maleate

CAS: 26328-04-1

Cinepazide maleate (MD-67350), a maleate salt form of cinepazide, is a vasodilator.

• Formula: C₂₂H₃₁N₃O₅·C₄H₄O₄
• Purity: 99.9% - 99.97%
• Color and Shape: White Or Off-White Crystalline Powder
• Molecular weight: 533.57

2-Propen-1-one, 1-[4-[2-oxo-2-(1-pyrrolidinyl)ethyl]-1-piperazinyl]-3-(3,4,5-trimethoxyphenyl)-, (2Z)-2-butenedioate (1:1)

CAS: 26328-04-1

• Formula: C₂₆H₃₅N₃O₉
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 533.5708

Cinepazide Maleate

CAS: 26328-04-1

• Purity: 99%
• Molecular weight: 533.57g/mol

Cinepazide Maleate

CAS: 26328-04-1

• Formula: C₂₂H₃₁N₃O₅·C₄H₄O₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 417.51 116.07

Cinepazide maleate

CAS: 26328-04-1

• Purity: 99.9%
• Molecular weight: 533.57g/mol

Cinepazide Maleate

CAS: 23887-46-9 26328-04-1

• Formula: C₂₂H₃₁N₃O₅·C₄H₄O₄
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow to Light orange powder to crystal
• Molecular weight: 533.58

Cinepazide Maleate

CAS: 26328-04-1

Applications Cinepazide Maleate, is a vasodilator used in China for the treatment of cardiovascular and …

• Formula: C₂₂H₃₁N₃O₅C₄H₄O₄
• Color and Shape: Neat
• Molecular weight: 417.22637

Cinepazidemaleate

CAS: 26328-04-1

Cinepazidemaleate is a drug used for the treatment of cerebral and coronary heart diseases. It …

• Formula: C₂₆H₃₅N₃O₉
• Purity: Min. 95%
• Molecular weight: 533.57 g/mol