CAS 263368-72-5

Boronic acid,(4-ethynylphenyl)- (9CI)

Description:

Boronic acid, (4-ethynylphenyl)-, also known by its CAS number 263368-72-5, is an organoboron compound characterized by the presence of a boronic acid functional group (-B(OH)2) attached to a phenyl ring that has an ethynyl substituent. This compound typically exhibits properties such as being a white to off-white solid at room temperature and is soluble in polar organic solvents. The presence of the ethynyl group enhances its reactivity, making it useful in various organic synthesis applications, particularly in cross-coupling reactions like Suzuki-Miyaura coupling, which is pivotal in forming carbon-carbon bonds. Boronic acids are known for their ability to form reversible complexes with diols, which can be exploited in sensor technology and drug delivery systems. Additionally, this compound may exhibit interesting electronic properties due to the conjugated system formed by the ethynyl group and the aromatic ring, making it a subject of interest in materials science and organic electronics. Safety data should be consulted for handling and storage, as with all chemical substances.

Formula: C₈H₇BO₂

Synonyms:

• Boronic acid, (4-ethynylphenyl)- (9CI)

Boronic acid, B-(4-ethynylphenyl)-

CAS: 263368-72-5

Formula: C₈H₇BO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 145.9510

Ref: IN-DA002SSK

4-(Dihydroxyborophenyl)acetylene

CAS: 263368-72-5

4-(Dihydroxyborophenyl)acetylene

Formula: C₈H₇BO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 145.95g/mol

Ref: 54-OR361136

4-Ethynylphenylboronic acid

CAS: 263368-72-5

Formula: C₈H₇BO₂

Purity: 98%

Molecular weight: 145.95

Ref: FT-E2056

(4-Ethynylphenyl)boronic acid

CAS: 263368-72-5

Purity: 95%

Molecular weight: 145.9499969

Ref: 10-F612756

4-(Dihydroxyborophenyl)acetylene

Controlled Product

CAS: 263368-72-5

Applications 4-(Dihydroxyborophenyl)acetylene is a reagent used in organic synthesis . It is used in the preparation of purine analogs as PI4K IIIβ inhibitors used in cancer treatment. As well, used in the preparation of demethylase inhibitors for their potential as anti-tumor drugs.
References Sala, M. et al. Bioorg. Med. Chem. Lett., 26, 2706 (2016); Wu, F. et al.: J. Med. Chem., 59, 253 (2016);

Formula: C₈H₇BO₂

Color and Shape: Neat

Molecular weight: 145.95

Ref: TR-D678935