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CAS 2641397-91-1

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  • Mrgx2 antagonist-3
    Targetmol
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    Mrgx2 antagonist-3

    CAS:
    <p>Mrgx2 antagonist-3 (Compound B-40) is a highly selective antagonist of the MrgX2 receptor, with an IC50 range of 0.042-2.5 nM. It blocks downstream G protein signaling and β-arrestin recruitment, inhibiting Mrgx2 receptor-mediated calcium influx and cell degranulation. Mrgx2 antagonist-3 shows potential for research in inflammation-associated diseases and pruritus, such as chronic urticaria and allergic asthma.</p>
    Formula:C15H15F2N3O
    Color and Shape:Solid
    Molecular weight:291.30

    Ref: TM-T207226