(R)-MrgprX2 antagonist-3, identified by its CAS number 2642174-20-5, is a chemical compound that functions as a selective antagonist for the Mas-related G protein-coupled receptor X2 (MrgprX2). This receptor is implicated in various physiological processes, including pain sensation and inflammatory responses. The compound is characterized by its specific stereochemistry, indicated by the "(R)" designation, which refers to the spatial arrangement of its atoms that can influence its biological activity and interaction with the target receptor. As an antagonist, (R)-MrgprX2 antagonist-3 inhibits the receptor's activity, potentially providing therapeutic benefits in conditions where MrgprX2 is involved, such as chronic pain or itch. The compound's pharmacological profile, including its potency, selectivity, and safety, would be critical for its development as a therapeutic agent. Further studies would typically focus on its efficacy in biological models and its potential side effects, as well as its pharmacokinetic properties, to assess its viability for clinical use.

(R)-MrgprX2 antagonist-3

2642174-20-5: (R)-MrgprX2 antagonist-3, identified by its CAS number 2642174-20-5, is a chemical compound that functions as a selective antagonist for the Mas-related G protein-coupled receptor X2 (MrgprX2). This receptor is implicated in various physiological processes, including pain sensation and inflammatory responses. The compound is characterized by its specific stereochemistry, indicated by the "(R)" designation, which refers to the spatial arrangement of its atoms that can influence its biological activity and interaction with the target receptor. As an antagonist, (R)-MrgprX2 antagonist-3 inhibits the receptor's activity, potentially providing therapeutic benefits in conditions where MrgprX2 is involved, such as chronic pain or itch. The compound's pharmacological profile, including its potency, selectivity, and safety, would be critical for its development as a therapeutic agent. Further studies would typically focus on its efficacy in biological models and its potential side effects, as well as its pharmacokinetic properties, to assess its viability for clinical use.

<p>(R)-MrgprX2 antagonist-3 is an antagonist of MrgprX2. It is applicable in the study of inflammatory skin diseases. For more detailed information, please refer to compound E118 in patent document WO2021092240A1.</p>

CAS 2642174-20-5

(R)-MrgprX2 antagonist-3

(R)-MrgprX2 antagonist-3

Ref: TM-T208997