Description:Phosphomycin calcium, with the CAS number 26472-47-9, is a calcium salt of phosphomycin, an antibiotic that is primarily used to treat bacterial infections. This compound exhibits broad-spectrum antibacterial activity, particularly against Gram-positive and some Gram-negative bacteria, by inhibiting cell wall synthesis. It functions by irreversibly binding to the enzyme MurA, which is crucial for the biosynthesis of peptidoglycan, a key component of bacterial cell walls. Phosphomycin calcium is typically administered in a form that allows for effective absorption and distribution in the body. It is often utilized in the treatment of urinary tract infections and other infections caused by susceptible organisms. The compound is generally well-tolerated, with a side effect profile that may include gastrointestinal disturbances. Its solubility and stability in various conditions make it suitable for pharmaceutical formulations. As with any antibiotic, appropriate use is essential to minimize the risk of resistance development.
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