CAS 2647503-57-7

2H-Benzimidazol-2-one, 5-[[5-chloro-2-[(3R,5S)-4,4-difluoro-3,5-dimethyl-1-piperidinyl]-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl-

Description:

2H-Benzimidazol-2-one, 5-[[5-chloro-2-[(3R,5S)-4,4-difluoro-3,5-dimethyl-1-piperidinyl]-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl- is a complex organic compound characterized by its multi-ring structure, which includes a benzimidazole moiety and a pyrimidine derivative. The presence of chlorine and difluoro groups suggests potential for significant biological activity, possibly influencing its pharmacological properties. The compound features a piperidine ring, which is often associated with various therapeutic effects, and a hydroxyl group that may enhance solubility and reactivity. Its molecular structure indicates potential interactions with biological targets, making it of interest in medicinal chemistry. The specific stereochemistry, denoted by the (3R,5S) configuration, may also play a crucial role in its biological activity and efficacy. Overall, this compound's unique combination of functional groups and structural features positions it as a candidate for further investigation in drug development and related fields.

Formula: C₂₄H₃₁ClF₂N₆O₂

Synonyms:

• 2H-Benzimidazol-2-one, 5-[[5-chloro-2-[(3R,5S)-4,4-difluoro-3,5-dimethyl-1-piperidinyl]-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl-

CCT369260

CAS: 2647503-57-7

CCT369260 (compound 1), an orally active inhibitor targeting B-cell lymphoma 6 (BCL6), demonstrates anti-tumor efficacy with an IC50 value of 520 nM [1].

Formula: C₂₄H₃₁ClF₂N₆O₂

Color and Shape: Solid

Molecular weight: 508.99

Ref: TM-T63503