CAS 26481-51-6

Tiprenolol

Description:

Tiprenolol is a beta-adrenergic antagonist, primarily used in the treatment of glaucoma and ocular hypertension. As a non-selective beta-blocker, it works by reducing intraocular pressure through decreased aqueous humor production. The chemical structure of Tiprenolol includes a naphthalene ring, which contributes to its pharmacological properties. It is typically administered in the form of eye drops, allowing for localized action with minimal systemic absorption. The substance exhibits a moderate solubility in water, which is essential for its formulation as an ophthalmic solution. Tiprenolol's mechanism of action involves blocking beta-adrenergic receptors, leading to a reduction in heart rate and contractility, although its primary application is in eye care. Side effects may include ocular irritation, dry eyes, and systemic effects such as bradycardia or hypotension, particularly in sensitive individuals. Overall, Tiprenolol represents an important therapeutic option in managing conditions related to elevated intraocular pressure.

Formula: C₁₃H₂₁NO₂S

InChI: InChI=1S/C13H21NO2S/c1-10(2)14-8-11(15)9-16-12-6-4-5-7-13(12)17-3/h4-7,10-11,14-15H,8-9H2,1-3H3

InChI key: InChIKey=CSUNLSYSEQIDMO-UHFFFAOYSA-N

SMILES: O(CC(CNC(C)C)O)C1=C(SC)C=CC=C1

Synonyms:

• 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(methylthio)phenoxy]-, (±)-
• 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(methylthio)phenoxy]-
• Tiprenolol
• 1-[(1-Methylethyl)amino]-3-[2-(methylthio)phenoxy]-2-propanol
• 2-Propanol, 1-(isopropylamino)-3-[o-(methylthio)phenoxy]-, (±)-

Tiprenolol

CAS: 26481-51-6

Tiprenolol

Purity: ≥95%

Molecular weight: 255.38g/mol

Ref: 54-BUP08444

Tiprenolol

CAS: 26481-51-6

Tiprenolol is a beta adrenergic receptor antagonist.[1]

Formula: C₁₃H₂₁NO₂S

Purity: 99.43%

Color and Shape: Solid

Molecular weight: 255.38

Ref: TM-T50081

1-[2-(Methylsulfanyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol

CAS: 26481-51-6

1-[2-(Methylsulfanyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol is a compound that has been shown to inhibit the production of proprotein convertase subtilisin/kexin type 9 (PCSK9), a protein that regulates cholesterol homeostasis. PCSK9 is an enzyme that cleaves the proprotein, converting it into its mature form. The inhibition of PCSK9 by 1-[2-(Methylsulfanyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol leads to increased levels of low density lipoprotein (LDL), which can be beneficial for the treatment of hypercholesterolemia and cardiovascular disease. In addition, this compound has been shown to have antihypertensive properties which may be due to its ability to lower blood pressure.

Formula: C₁₃H₂₁NO₂S

Purity: Min. 95%

Molecular weight: 255.38 g/mol

Ref: 3D-BBA48151