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CAS 2648407-76-3

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  • GT-02216

    CAS:
    GT-02216 is capable of binding allosterically to GCase, thereby enhancing its function. In primary human fibroblasts, it increases GCase activity and decreases Tau accumulation in mutant GBA1 fibroblasts. Additionally, GT-02216 offers protection to hippocampal primary neurons exposed to Tau oligomer in a rat model.
    Formula:C22H23N5O2
    Color and Shape:Solid
    Molecular weight:389.45