CAS 2648799-49-7

2H-Indol-2-one, 3-[(3E)-1,3-dihydro-3-[[2-oxo-2-(1-piperazinyl)ethoxy]imino]-2H-indol-2-ylidene]-1,3-dihydro-, (3Z)-

Description:

2H-Indol-2-one, 3-[(3E)-1,3-dihydro-3-[[2-oxo-2-(1-piperazinyl)ethoxy]imino]-2H-indol-2-ylidene]-1,3-dihydro-, (3Z)-, identified by CAS number 2648799-49-7, is a complex organic compound characterized by its indole core structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. This substance features multiple functional groups, including an imine and a piperazine moiety, which contribute to its potential biological activity. The presence of the indole and piperazine structures suggests that it may exhibit pharmacological properties, possibly acting as a ligand for various biological targets. The stereochemistry indicated by the (3E) and (3Z) descriptors suggests specific geometric configurations that can influence the compound's reactivity and interaction with biological systems. Overall, this compound's intricate structure positions it as a candidate for further research in medicinal chemistry and drug development, particularly in the context of its potential therapeutic applications.

Formula: C₂₂H₂₁N₅O₃

Synonyms:

• FLT3/D835Y-IN-1
• 2H-Indol-2-one, 3-[(3E)-1,3-dihydro-3-[[2-oxo-2-(1-piperazinyl)ethoxy]imino]-2H-indol-2-ylidene]-1,3-dihydro-, (3Z)-

FLT3/D835Y-IN-1

CAS: 2648799-49-7

FLT3/D835Y-IN-1, an oral FLT3 inhibitor (IC50: FLT3 - 0.26 nM, D835Y - 0.18 nM), shows anticancer potential in AML research.

Formula: C₂₂H₂₁N₅O₃

Color and Shape: Solid

Molecular weight: 403.43

Ref: TM-T61977