CAS 2648853-26-1

1H-Indole-2-carboxamide, 4,5,6,7-tetrahydro-3,6,6-trimethyl-N-[(1S)-1-[[[4-[(1-methyl-4-piperidinyl)oxy]phenyl]amino]carbonyl]pentyl]-4-oxo-

Description:

1H-Indole-2-carboxamide, 4,5,6,7-tetrahydro-3,6,6-trimethyl-N-[(1S)-1-[[[4-[(1-methyl-4-piperidinyl)oxy]phenyl]amino]carbonyl]pentyl]-4-oxo- is a complex organic compound characterized by its indole core structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. This substance features multiple functional groups, including a carboxamide and a piperidine moiety, contributing to its potential biological activity. The presence of the tetrahydro and trimethyl groups indicates a degree of saturation and steric hindrance, which may influence its pharmacokinetic properties. The compound's structure suggests it may interact with various biological targets, making it of interest in medicinal chemistry. Its CAS number, 2648853-26-1, allows for precise identification in chemical databases. Overall, this compound's unique structural features may confer specific properties, such as solubility, stability, and reactivity, which are essential for its potential applications in drug development or other chemical research.

Formula: C₃₀H₄₂N₄O₄

Synonyms:

• 1H-Indole-2-carboxamide, 4,5,6,7-tetrahydro-3,6,6-trimethyl-N-[(1S)-1-[[[4-[(1-methyl-4-piperidinyl)oxy]phenyl]amino]carbonyl]pentyl]-4-oxo-
• G9a-IN-2

G9a-IN-2

CAS: 2648853-26-1

G9a-IN-2 (Compound 7i) is an inhibitor of the histone methyltransferase G9a, with an IC50 of 0.024 μM. It can reduce the levels of H3K9me2 and induce the expression of γ-globin mRNA. G9a-IN-2 shows potential for improving Sickle Cell Disease (SCD).

Formula: C₃₀H₄₂N₄O₄

Color and Shape: Solid

Molecular weight: 522.68

Ref: TM-T88804