CAS 26530-03-0

3(2H)-Isothiazolone, 5-chloro-2-methyl-, hydrochloride (1:1)

Description:

3(2H)-Isothiazolone, 5-chloro-2-methyl-, hydrochloride (1:1), commonly known as chloromethylisothiazolone, is a synthetic organic compound primarily used as a biocide and preservative in various industrial applications, including paints, coatings, and personal care products. It is characterized by its isothiazolone structure, which features a five-membered ring containing both sulfur and nitrogen atoms, contributing to its antimicrobial properties. The compound is typically a white to off-white solid and is soluble in water and organic solvents, making it versatile for formulation in different products. It exhibits broad-spectrum efficacy against bacteria, fungi, and algae, which makes it valuable in preventing microbial growth. However, it is important to note that isothiazolone derivatives can be sensitizing agents and may cause allergic reactions in some individuals. Therefore, safety precautions are essential when handling this compound, and regulatory guidelines should be followed to minimize exposure risks.

Formula: C₄H₅Cl₂NOS

InChI: InChI=1/C4H4ClNOS.ClH/c1-6-4(7)2-3(5)8-6;/h2H,1H3;1H

InChI key: InChIKey=RGVYUPIYFIVQDS-UHFFFAOYSA-N

SMILES: O=C1N(C)SC(Cl)=C1.Cl

Synonyms:

• 3(2H)-Isothiazolone, 5-chloro-2-methyl-, hydrochloride
• 3(2H)-Isothiazolone, 5-chloro-2-methyl-, hydrochloride (1:1)
• 4-Isothiazolin-3-one, 5-chloro-2-methyl-, hydrochloride
• 5-Chloro-2-methyl-3-isothiazolone hydrochloride
• 5-Chloro-2-methyl-4-isothiazolin-3-one hydrochloride
• 5-Chloro-2-methyl-2H-isothiazol-3-one hydrochloride
• 5-chloro-2-Methyl-2h-isothiazol-3-one hydrochloride (95.7%)
• 5-chloro-2-methylisothiazol-3(2H)-one hydrochloride
• 5-Chloro-2-Methyl-2H-isothiazol-3-one hydrochlorid
• 2-[[[3-(ethylcarbamoyl)-5-[ethyl(1-oxopropyl)amino]-2,4,6-triiodophenyl]-oxomethyl]amino]acetic acid

5-Chloro-2-methyl-2H-isothiazol-3-one hydrochloride

CAS: 26530-03-0

5-Chloro-2-methyl-2H-isothiazol-3-one hydrochloride (Kathon CG) is a preservative that belongs to the group of sesquiterpene lactones. It is used in cosmetics, pharmaceuticals, and industrial products as an antimicrobial agent. Kathon CG has been shown to be effective against bacteria such as Escherichia coli and Staphylococcus aureus. Kathon CG has also been found to be nontoxic to human cells in vitro at concentrations up to 100%. The optimum concentration for this preservative has been found to be 0.0025% in vivo on human skin and 0.025% in vitro on human skin. This preservative is not toxic to humans or animals when ingested at doses up to 2 g/kg body weight and can cause dermatitis at concentrations of 10%.

Formula: C₄H₅Cl₂NOS

Purity: Min. 95 Area-%

Color and Shape: Red Powder

Molecular weight: 186.06 g/mol

Ref: 3D-FC150177