CAS 26575-95-1

Alisol B acetate

Description:

Alisol B acetate is a chemical compound classified as a triterpenoid, specifically derived from the plant Alisma orientale, commonly known as the Chinese water plantain. It is characterized by its complex tetracyclic structure, which contributes to its biological activity. Alisol B acetate is known for its potential pharmacological properties, including anti-inflammatory, hepatoprotective, and diuretic effects, making it of interest in traditional medicine and modern pharmacology. The compound is typically found in the form of a white to off-white powder and is soluble in organic solvents such as ethanol and methanol, but has limited solubility in water. Its molecular formula reflects a specific arrangement of carbon, hydrogen, and oxygen atoms, which is crucial for its biological interactions. Alisol B acetate is often studied for its potential therapeutic applications, particularly in the context of metabolic disorders and liver health. As with many natural products, further research is ongoing to fully elucidate its mechanisms of action and potential uses in medicine.

Formula: C₃₂H₅₀O₅

InChI: InChI=1/C32H50O5/c1-18(16-23(36-19(2)33)27-29(5,6)37-27)20-10-14-31(8)21(20)17-22(34)26-30(7)13-12-25(35)28(3,4)24(30)11-15-32(26,31)9/h18,22-24,26-27,34H,10-17H2,1-9H3/t18-,22+,23+,24+,26+,27-,30+,31+,32+/m1/s1

Synonyms:

• (23S,24R)-24,25-Epoxy-11b,23-dihydroxy-8a,9b,14b-dammar-13(17)-en-3-one 23-acetate
• (5Xi,8Alpha,9Xi,11Beta,14Beta,20Xi)-11-Hydroxy-3-Oxo-24,25-Epoxydammar-13(17)-En-23-Yl Acetate
• Alisol B 23-acetate

Dammar-13(17)-en-3-one, 23-(acetyloxy)-24,25-epoxy-11-hydroxy-, (8α,9β,11β,14β,23S,24R)-

CAS: 26575-95-1

Formula: C₃₂H₅₀O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 514.7364

Ref: IN-DA002TR8

Alisol B 23-acetate

CAS: 26575-95-1

Alisol B 23-acetate

Purity: ≥98%

Molecular weight: 514.74g/mol

Ref: 54-BUP06385

Alisol B Acetate

CAS: 26575-95-1

Formula: C₃₂H₅₀O₅

Molecular weight: 514.75

Ref: 7W-GY2596

Alisol B Acetate

CAS: 26575-95-1

Alisol B 23-acetate, a partial non-competitive inhibitor of P-gp, it may be a potential MDR reversal agent. Alisol B 23-acetate produces protective effects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated gene regulation; it obviously inhibits proliferation of the three ovarian cancer cell lines, possesses anti-proliferation, anti-migration and anti-invasion activities as a single agent on ovarian cancer cells.

Formula: C₃₂H₅₀O₅

Purity: 95%~99%

Molecular weight: 514.747

Ref: BP-BP0136

Alisol B 23-Acetate

CAS: 26575-95-1

Formula: C₃₂H₅₀O₅

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 514.75

Ref: 3B-A3606

Alisol B 23-acetate

CAS: 26575-95-1

Alisol B 23-acetate shields the liver from toxins and aids regeneration via FXR and STAT3 gene regulation.

Formula: C₃₂H₅₀O₅

Purity: 99.87% - 99.95%

Color and Shape: Solid

Molecular weight: 514.74

Ref: TM-T6S2246

Alisol b 23-acetate

CAS: 26575-95-1

Acetic acid ester

Formula: C₃₂H₅₀O₅

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 514.74

Ref: 5G-82464

Alisol B 23-Acetate

Controlled Product

CAS: 26575-95-1

Applications Alisol B 23-Acetate is effective in reversing the multi-drug resistance of specific over-expressing P-glycoprotein cancer cells. An herbal triterpene extract that is useful in the treatment of cancers, primarily prostate cancer.
References Wang, C. et al.: Biochem. Pharm., 68, 843 (2004); Huang, Y. et al.: Canc. Lett., 231, 270 (2006);

Formula: C₃₂H₅₀O₅

Color and Shape: Neat

Molecular weight: 514.74

Ref: TR-A535970

Alisol B 23-acetate

CAS: 26575-95-1

Alisol B is a natural compound that has been shown to have significant cytotoxicity in vitro. Alisol B also inhibits the mitochondrial membrane potential, which is vital for cell survival. Alisol B is found to be active against several human cancer cell lines, including leukemia and breast cancer cells. It has also been shown to inhibit autophagy, the process by which cells degrade their own components and organelles in response to starvation or other stresses. This inhibition of autophagy leads to increased cell death. The anti-cancer effects of Alisol B are mediated through a number of different mechanisms, including the inhibition of protein synthesis and the induction of apoptosis. Alisol B has also been shown to have hepatoprotective properties in animal models.

Formula: C₃₂H₅₀O₅

Purity: Min. 95%

Molecular weight: 514.74 g/mol

Ref: 3D-FA73774