CAS 26577-85-5

(+)-Petasin

Description:

(+)-Petasin, with the CAS number 26577-85-5, is a natural compound primarily derived from the plant Petasites hybridus, commonly known as butterbur. It belongs to the class of sesquiterpene lactones, which are characterized by their unique cyclic structures and biological activity. This compound is known for its anti-inflammatory and analgesic properties, making it of interest in herbal medicine and pharmacology. (+)-Petasin exhibits a chiral center, resulting in its specific optical activity, which is denoted by the "+" sign in its name. The substance is typically found in the form of a colorless to pale yellow oil and has a distinct odor. Its solubility is generally higher in organic solvents than in water, which is a common trait among many sesquiterpene compounds. Research has indicated that (+)-Petasin may also possess potential benefits in treating migraines and other conditions, although further studies are necessary to fully understand its mechanisms and efficacy.

Formula: C₂₀H₂₈O₃

InChI: InChI=1/C20H28O3/c1-7-13(4)19(22)23-18-9-8-15-10-17(21)16(12(2)3)11-20(15,6)14(18)5/h7,10,14,16,18H,2,8-9,11H2,1,3-6H3/b13-7-/t14-,16-,18+,20+/m0/s1

InChI key: InChIKey=ISTBXSFGFOYLTM-NZEDGPFZSA-N

SMILES: C[C@@]12C(=CC(=O)[C@H](C(C)=C)C1)CC[C@@H](OC(/C(=C\C)/C)=O)[C@@H]2C

Synonyms:

• 2-Butenoic acid, 2-methyl-, 1,2,3,4,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)-6-oxo-2-naphthalenyl ester, [1R-[1α,2β(Z),7β,8aα]]-
• Petasin
• Crotonic acid, 2-methyl-, ester with 3α-hydroxy-eremophila-9,11-dien-8-one, (Z)-
• 2-Butenoic acid, 2-methyl-, (1R,2R,7S,8aR)-1,2,3,4,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)-6-oxo-2-naphthalenyl ester, (2Z)-
• Eremophila-9,11-dien-8-one, 3α-hydroxy-, 2-methylcrotonate, (Z)-
• O-Angeloylsencathenone
• (Z)-2-Methyl-2-butenoic acid [(3S)-3α-isopropenyl-4aβ,5β-dimethyl-2,3,4,4a,5,6,7,8-octahydro-2-oxonaphthalene]-6α-yl ester
• (Z)-2-Methyl-2-butenoic acid (1R)-1,2,3,4,6,7,8,8a-octahydro-1β,8aβ-dimethyl-7α-(1-methylethenyl)-6-oxonaphthalen-2α-yl ester
• Petaforce
• (2Z)-2-Methyl-2-butenoic acid (1R,2R,7S,8aR)-1,2,3,4,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)-6-oxo-2-naphthalenyl ester

2-Butenoic acid, 2-methyl-, (1R,2R,7S,8aR)-1,2,3,4,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)-6-oxo-2-naphthalenyl ester, (2Z)-

CAS: 26577-85-5

Formula: C₂₀H₂₈O₃

Molecular weight: 316.4345

Ref: IN-DA002TQZ

Petasin

CAS: 26577-85-5

Formula: C₂₀H₂₈O₃

Molecular weight: 316.44

Ref: 4Z-P-223001

Petasin

CAS: 26577-85-5

Petasin is a natural extract, which is derived from the butterbur plant (Petasites hybridus) with mechanisms involving leukotriene biosynthesis inhibition. This compound acts primarily by suppressing the action of the enzyme 5-lipoxygenase, which is responsible for the production of leukotrienes, potent mediators of inflammation. By inhibiting leukotriene synthesis, Petasin exerts significant anti-inflammatory and anti-spasmodic effects at a molecular level.

Formula: C₂₀H₂₈O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 316.44 g/mol

Ref: 3D-XP173205