CAS 265989-32-0

(2E)-4-methyl-3-oxo-2-[(2,3,4,5,6-pentadeuteriophenyl)methylene]-N-phenyl-pentanamide

Description:

The chemical substance known as (2E)-4-methyl-3-oxo-2-[(2,3,4,5,6-pentadeuteriophenyl)methylene]-N-phenyl-pentanamide, with the CAS number 265989-32-0, is a synthetic organic compound characterized by its complex structure, which includes a pentanamide backbone, a ketone functional group, and a substituted phenyl group. The presence of deuterium in the phenyl ring indicates that this compound is isotopically labeled, which can be useful in various research applications, including studies involving metabolic pathways or pharmacokinetics. The compound's E configuration at the double bond suggests a specific geometric arrangement that can influence its reactivity and interactions with biological targets. Its molecular structure likely contributes to its potential biological activity, making it of interest in medicinal chemistry. Additionally, the presence of multiple functional groups suggests that it may participate in various chemical reactions, including hydrogen bonding and electrophilic interactions, which are critical for its behavior in biological systems. Overall, this compound exemplifies the complexity and diversity of synthetic organic molecules used in research and development.

Formula: C₁₉H₁₄D₅NO₂

InChI: InChI=1/C19H19NO2/c1-14(2)18(21)17(13-15-9-5-3-6-10-15)19(22)20-16-11-7-4-8-12-16/h3-14H,1-2H3,(H,20,22)/b17-13+/i3D,5D,6D,9D,10D

2-Isobutyryl-N-phenyl-3-phenylacrylamide

Controlled Product

CAS: 265989-32-0

Applications 2-Isobutyryl-N-phenyl-3-phenylacrylamide is the labeled analogue of 2-Isobutyryl-N-phenyl-3-phenylacrylamide (I781040), an intermediate for the synthesis of Atorvastatin-d5 Sodium Salt (A791753), the labeled analogue of Atorvastatin (A791750) (1,2,3). Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References (1) Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993) (2) Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996) (3) Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)

Formula: C₁₉H₁₄D₅NO₂

Color and Shape: Neat

Molecular weight: 298.39

Ref: TR-I781042

Pentanamide, 4-methyl-3-oxo-N-(phenyl-d5)-2-(phenylmethylene)- (9CI)

CAS: 265989-32-0

Formula: C₁₉H₁₄D₅NO₂

Molecular weight: 298.3905

Ref: IN-DA002TTO