CAS 265989-49-9

para-Hydroxy Atorvastatin-d5 Lactone

CAS: 265989-49-9

Formula: C₃₃H₂₈FN₂O₅D₅

Color and Shape: White To Off-White Solid

Molecular weight: 561.67

Ref: 4Z-A-131

4-Hydroxy Atorvastatin Lactone-d5

Controlled Product

CAS: 265989-49-9

Applications A labelled metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.

Formula: C₃₃₂H₅H₂₈FN₂O₅

Color and Shape: Neat

Molecular weight: 561.65

Ref: TR-H828964

4-Hydroxy atorvastatin lactone-d5

CAS: 265989-49-9

4-Hydroxy atorvastatin lactone-d5 is a stable isotope that is used to characterize the 3-hydroxy-3-methylglutaryl-coa reductase (HMGCR) inhibition constant of atorvastatin. It is used for calibration and quantification in the analysis of atorvastatin in human liver supernatants and interactions with cytochrome P450 enzymes. The high degree of hydrophilicity of 4-hydroxy atorvastatin lactone-d5 makes it suitable for hydrophilic interaction chromatography (HILIC) separation.

Formula: C₃₃H₃₃FN₂O₅

Purity: Min. 95%

Molecular weight: 556.6 g/mol

Ref: 3D-QKA98949