CAS 26607-15-8

L-Leucyl-L-arginine

Description:

L-Leucyl-L-arginine is a dipeptide composed of the amino acids leucine and arginine, linked by a peptide bond. It is characterized by its role in various biological processes, including protein synthesis and cellular signaling. This compound exhibits properties typical of peptides, such as solubility in water and stability under physiological conditions. L-Leucyl-L-arginine can influence metabolic pathways and has been studied for its potential effects on immune function and muscle metabolism. The presence of the basic amino acid arginine contributes to its physiological activity, as arginine is known to be a precursor for nitric oxide synthesis, which plays a crucial role in vasodilation and blood flow regulation. Additionally, the hydrophobic nature of leucine may affect the peptide's interactions with cell membranes and proteins. Overall, L-Leucyl-L-arginine serves as an important molecule in biochemistry and pharmacology, with ongoing research exploring its therapeutic applications.

Formula: C₁₂H₂₅N₅O₃

InChI: InChI=1/C12H25N5O3/c1-7(2)6-8(13)10(18)17-9(11(19)20)4-3-5-16-12(14)15/h7-9H,3-6,13H2,1-2H3,(H,17,18)(H,19,20)(H4,14,15,16)

InChI key: InChIKey=SENJXOPIZNYLHU-IUCAKERBSA-N

SMILES: [C@H](NC([C@H](CC(C)C)N)=O)(CCCNC(=N)N)C(O)=O

Synonyms:

• 124: PN: WO2009132287 SEQID: 194 claimed protein
• 1707: PN: WO2007124090 PAGE: 83 claimed protein
• 175: PN: WO2011032181 SEQID: 194 unclaimed protein
• 182: PN: WO2009114815 SEQID: 194 unclaimed protein
• 205: PN: WO2010059829 SEQID: 223 unclaimed protein
• 26: PN: EP2161028 PAGE: 10 claimed protein
• 44: PN: WO2010045512 SEQID: 43 unclaimed protein
• 522: PN: WO2010124259 SEQID: 551 claimed protein
• 525: PN: WO2010124262 SEQID: 551 claimed protein
• 78: PN: US20070066537 PAGE: 17 claimed protein
• <span class="text-smallcaps">L</smallcap>-Arginine, <smallcap>L</span>-leucyl-
• <span class="text-smallcaps">L</smallcap>-Arginine, N²-<smallcap>L</span>-leucyl-
• <span class="text-smallcaps">L</smallcap>-Leucyl-<smallcap>L</span>-arginine
• Arginine, N²-<span class="text-smallcaps">L</smallcap>-leucyl-, <smallcap>L</span>-
• H-Leu-Arg-OH
• L-leucyl-N~5~-(diaminomethylidene)-L-ornithine
• leucyl-N~5~-(diaminomethylidene)ornithine
• Arginine, N2-L-leucyl-, L-
• L-Arginine, N2-L-leucyl-
• L-Arginine, L-leucyl-
• L-Leucyl-L-arginine
• Leu-Arg-OH
• L-Leu-L-Arg-OH
• leu-arg acetate
• Nα-L-Leucyl-L-arginine
• LEU-ARG ACETATE SALT
• H-LEU-ARG-OH ACETATE SALT
• leucylarginine

H-Leu-Arg-OH

CAS: 26607-15-8

Bachem ID: 4003808.

Formula: C₁₂H₂₅N₅O₃

Purity: > 98%

Color and Shape: White Powder

Molecular weight: 287.36

Ref: 01-4003808

L-Leucyl-L-arginine

CAS: 26607-15-8

Formula: C₁₂H₂₅N₅O₃

Color and Shape: Solid

Molecular weight: 287.3586

Ref: IN-DA019FW6

Leucylarginine

CAS: 26607-15-8

Leucylarginine hinders antinociception induced by L-arginine.

Formula: C₁₂H₂₅N₅O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 287.36

Ref: TM-T25684

H-Leu-Arg-OH acetate salt

CAS: 26607-15-8

H-Leu-Arg-OH acetate salt is a cyclase inhibitor that is used to treat cancer. It has been shown to inhibit soluble guanylate cyclase, which is an enzyme that converts guanosine triphosphate (GTP) into the second messenger molecule, cyclic guanosine monophosphate (cGMP). Inhibition of this enzyme results in a decrease in the production of cGMP and blood pressure. H-Leu-Arg-OH acetate salt also inhibits delta opioid receptors, which are found on the surface of cells in the brain. This drug binds competitively with delta opioid receptors and blocks the effect of endogenous or exogenous ligands such as enkephalins.

Formula: C₁₂H₂₅N₅O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 287.36 g/mol

Ref: 3D-FL108087