CAS 266320-83-6

2-(3,4-Difluorophenyl)-4-(3-hydroxy-3-methylbutoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone

Description:

2-(3,4-Difluorophenyl)-4-(3-hydroxy-3-methylbutoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone, with CAS number 266320-83-6, is a synthetic organic compound characterized by its complex structure, which includes a pyridazinone core. This compound features multiple functional groups, including a difluorophenyl moiety, a hydroxy group, and a methylsulfonyl group, contributing to its potential biological activity. The presence of the difluorophenyl group may enhance lipophilicity and influence the compound's interaction with biological targets. The hydroxy group can participate in hydrogen bonding, potentially affecting solubility and reactivity. Additionally, the methylsulfonyl group is known for its role in enhancing metabolic stability and bioavailability. Overall, this compound may exhibit interesting pharmacological properties, making it a candidate for further research in medicinal chemistry and drug development. However, specific biological activities, toxicity, and therapeutic applications would require detailed experimental studies to elucidate its potential uses.

Formula: C₂₂H₂₂F₂N₂O₅S

InChI: InChI=1S/C22H22F2N2O5S/c1-22(2,28)10-11-31-20-17(14-4-7-16(8-5-14)32(3,29)30)13-25-26(21(20)27)15-6-9-18(23)19(24)12-15/h4-9,12-13,28H,10-11H2,1-3H3

InChI key: InChIKey=XNTLXAUHLBBEKP-UHFFFAOYSA-N

SMILES: O(CCC(C)(C)O)C1=C(C=NN(C1=O)C2=CC(F)=C(F)C=C2)C3=CC=C(S(C)(=O)=O)C=C3

Synonyms:

• 3(2H)-Pyridazinone, 2-(3,4-difluorophenyl)-4-(3-hydroxy-3-methylbutoxy)-5-[4-(methylsulfonyl)phenyl]-
• ABT 963
• 4-(3-Hydroxy-3-methylbutoxy)-5-[4-(methylsulfonyl)phenyl]-2-(3,4-difluorophenyl)pyridazin-3(2H)-one
• 2-(3,4-Difluorophenyl)-4-(3-hydroxy-3-methylbutoxy)-5-[4-(methylsulfonyl)phenyl]-3-2H-pyridazinone
• 2-(3,4-Difluorophenyl)-4-(3-hydroxy-3-methylbutoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone

2-(3,4-Difluorophenyl)-4-(3-hydroxy-3-methylbutoxy)-5-(4-(methylsulfonyl)phenyl)pyridazin-3(2H)-one

CAS: 266320-83-6

Formula: C₂₂H₂₂F₂N₂O₅S

Purity: 95%

Molecular weight: 464.4823

Ref: IN-DA002TWD

ABT-963

CAS: 266320-83-6

ABT-963

Purity: ≥95%

Molecular weight: 464.48g/mol

Ref: 54-BUP03358

ABT-963

CAS: 266320-83-6

ABT-963: COX-2 inhibitor for osteoarthritis/pain with high selectivity, potency, and gastric safety.

Formula: C₂₂H₂₂F₂N₂O₅S

Purity: 98% - 99.85%

Color and Shape: Solid

Molecular weight: 464.48

Ref: TM-T26531