CAS 266359-83-5
:Repertaxin
Description:
Repertaxin, identified by its CAS number 266359-83-5, is a chemical compound known for its role as a selective antagonist of the chemokine receptor CXCR2. This receptor is involved in various inflammatory processes and is a target for therapeutic intervention in conditions such as chronic obstructive pulmonary disease (COPD) and other inflammatory diseases. Repertaxin exhibits properties that allow it to inhibit the binding of chemokines to CXCR2, thereby modulating the inflammatory response. The compound is characterized by its specific molecular structure, which contributes to its biological activity and selectivity. In terms of physical properties, Repertaxin is typically presented as a solid at room temperature, with solubility in organic solvents. Its pharmacokinetic profile includes considerations of absorption, distribution, metabolism, and excretion, which are crucial for its efficacy and safety in clinical applications. Overall, Repertaxin represents a significant advancement in the development of targeted therapies for inflammatory conditions.
Formula:C14H21NO3S
InChI:InChI=1S/C14H21NO3S/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15-19(4,17)18/h5-8,10-11H,9H2,1-4H3,(H,15,16)/t11-/m1/s1
InChI key:InChIKey=KQDRVXQXKZXMHP-LLVKDONJSA-N
SMILES:[C@@H](C(NS(C)(=O)=O)=O)(C)C1=CC=C(CC(C)C)C=C1
Synonyms:- Reparixin
- (αR)-α-Methyl-4-(2-methylpropyl)-N-(methylsulfonyl)benzeneacetamide
- Repertaxin
- Benzeneacetamide, α-methyl-4-(2-methylpropyl)-N-(methylsulfonyl)-, (αR)-
- DF 1681Y
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Found 5 products.
(R)-2-(4-Isobutylphenyl)-N-(Methylsulfonyl)Propanamide
CAS:(R)-2-(4-Isobutylphenyl)-N-(Methylsulfonyl)PropanamidePurity:98%Molecular weight:283.39g/molReparixin
CAS:<p>Reparixin inhibits CXCR1 (IC50=1 nM) strongly, CXCR2 weakly (IC50=100 nM), and it's a CXCL8 receptor blocker.</p>Formula:C14H21NO3SPurity:98% - 99.89%Color and Shape:SolidMolecular weight:283.39
