CAS 26662-91-9

POPC

Description:

POPC, or 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, is a phospholipid commonly used in biochemistry and cell biology. It is characterized by its amphiphilic nature, possessing both hydrophilic (water-attracting) and hydrophobic (water-repelling) regions, which allows it to form bilayers and vesicles in aqueous environments. POPC is a major component of biological membranes and is often utilized in the study of membrane dynamics, lipid bilayer properties, and membrane protein interactions. Its structure includes a palmitic acid (saturated fatty acid) and an oleic acid (unsaturated fatty acid) moiety, contributing to its fluidity and stability in lipid bilayers. POPC is also used in liposome formulations for drug delivery and as a model membrane system in various experimental setups. Its ability to mimic natural cell membranes makes it a valuable tool in research related to membrane biophysics and pharmacology.

Formula: C₄₂H₈₂NO₈P

InChI: InChI=1/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-

InChI key: InChIKey=WTJKGGKOPKCXLL-MRCUWXFGNA-N

SMILES: C(OC(CCCCCCC/C=C\CCCCCCCC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCCCCCCCCCC)=O

Synonyms:

• 2-Oleo-1-palmitin phosphate choline ester
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1-palmito-2-olein, DL-
• rac-1-Palmitoyl-2-oleoylglycero-3-phosphorylcholine
• 3,5,8-Trioxa-4-phosphahexacos-17-en-1-aminium, 4-hydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-, inner salt, 4-oxide, (Z)-(±)-
• 3,5,8-Trioxa-4-phosphahexacos-17-en-1-aminium, 4-hydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-, inner salt, 4-oxide, (17Z)-

(Rac)-POPC

CAS: 26662-91-9

(Rac)-POPC serves as a model phosphatidylcholine utilized in the preparation of giant vesicles (GVs) [1].

Formula: C₄₂H₈₂NO₈P

Color and Shape: Solid

Molecular weight: 760.08

Ref: TM-T74242