CAS 26662-94-2

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine

Description:

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine, commonly referred to as POPE, is a phospholipid that plays a crucial role in cellular membranes, particularly in the formation of lipid bilayers. It is characterized by its amphiphilic nature, possessing both hydrophilic (the phosphoethanolamine head group) and hydrophobic (the fatty acid tails) regions, which facilitates its integration into lipid membranes. The structure includes a saturated palmitoyl chain and an unsaturated oleoyl chain, contributing to its fluidity and stability in membrane environments. POPE is often used in biophysical studies and in the formulation of liposomes for drug delivery due to its biocompatibility and ability to form stable vesicles. Additionally, it is involved in various biological processes, including membrane fusion and signaling pathways. Its CAS number, 26662-94-2, is a unique identifier that helps in the cataloging and referencing of this specific chemical substance in scientific literature and databases.

Formula: C₃₉H₇₆NO₈P

InChI: InChI=1S/C39H76NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)48-37(36-47-49(43,44)46-34-33-40)35-45-38(41)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,37H,3-16,19-36,40H2,1-2H3,(H,43,44)/b18-17-/t37-/m1/s1

InChI key: InChIKey=FHQVHHIBKUMWTI-OTMQOFQLSA-N

SMILES: [C@@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)(COC(CCCCCCCCCCCCCCC)=O)COP(OCCN)(=O)O

Synonyms:

• (R)-1-((((2-Aminoethoxy)hydroxyphosphinyl)oxy)methyl)-2-((1-oxohexadecyl)oxy)ethyl oleate
• 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine
• 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphorylethanolamine
• 1-Palmitoyl-2-oleoyl-sn-glyceryl-3-phosphorylethanolamine
• 1-Palmitoyl-2-oleoylphosphatidylethanolamine
• 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphatidylethanolamine
• 9-Octadecenoic acid (9Z)-, (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester
• 9-Octadecenoic acid (Z)-, 1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester, (R)-
• <span class="text-smallcaps">L</span>-α-1-Palmitoyl-2-oleoylglycerophosphoethanolamine
• Ethanol, 2-amino-, dihydrogen phosphate (ester) monoester with 1-palmito-2-olein, <span class="text-smallcaps">L</span>-
• Olein, 1-palmito-2-, dihydrogen phosphate mono(2-aminoethyl) ester, <span class="text-smallcaps">L</span>-
• Palmitin, 2-oleo-1-, dihydrogen phosphate mono(2-aminoethyl) ester, <span class="text-smallcaps">L</span>-
• Pe(16:0/18:1(9Z))
• Phosphatidyl-β-oleoyl-γ-palmitoyl ethanolamine
• Phosphatidylethanolamine (16:0/18:1)
• Olein, 1-palmito-2-, dihydrogen phosphate mono(2-aminoethyl) ester, L-
• Palmitin, 2-oleo-1-, dihydrogen phosphate mono(2-aminoethyl) ester, L-

POPE

CAS: 26662-94-2

POPE(1-Palmitoyl-2-oleoyl-sn-glycero-3-PE) is a compound found in Escherichia coli, part of the cell membrane, and can be used to study changes in cell membrane permeability.

Formula: C₃₉H₇₆NO₈P

Purity: 97% - 98.02%

Color and Shape: Solid

Molecular weight: 718

Ref: TM-TF0083

1-HEXADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

CAS: 26662-94-2

Formula: C₃₉H₇₆NO₈P

Purity: 97%

Color and Shape: Solid

Molecular weight: 717.9964

Ref: IN-DA00BG77

2-Oleoyl-1-Palmitoyl-sn-Glycero-3-Phosphoethanolamine

CAS: 26662-94-2

2-Oleoyl-1-Palmitoyl-sn-Glycero-3-Phosphoethanolamine

Purity: 97%

Molecular weight: 718.00g/mol

Ref: 54-OR1010577

POPE

CAS: 26662-94-2

POPE

Purity: ≥95%

Molecular weight: 718g/mol

Ref: 54-BUP11134

1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphatidylethanolamine

CAS: 26662-94-2

Formula: C39H76NO8P

Purity: >98%

Color and Shape: Solid

Molecular weight: 718

Ref: 48-37-1828

1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphoethanolamine

CAS: 26662-94-2

Formula: C₃₉H₇₆NO₈P

Molecular weight: 718.01

Ref: 4Z-P-312001

POPE

Controlled Product

CAS: 26662-94-2

Stability Light Sensitive, Moisture Sensitive
Applications POPE is a component of E. Coli bacteria cell membrane.
References Tu, Y., et al.: Nature Nanotechnology, 8, 594 (2013).

Formula: C₃₉H₇₆NO₈P

Color and Shape: Neat

Molecular weight: 718.0

Ref: TR-P689510

1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphatidylethanolamine

CAS: 26662-94-2

1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphatidylethanolamine is a broad spectrum antimicrobial that has been shown to have binding properties to peptides. This compound can be used as a potential antimicrobial for the treatment of bacterial infections and gramicidin, an antibiotic that is active against bacteria. It has also been shown to permeabilize cell membranes, which may lead to its function as an antimicrobial agent. 1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphatidylethanolamine is water soluble and has been shown to have conformational properties. These conformational properties are responsible for its binding activity with peptides. 1POGPE is stable in both calorimetric assays and bilayers, which allows it to maintain its structure when interacting with other compounds. 1POGPE also has a high affinity for

Formula: C₃₉H₇₆NO₈P

Purity: Min. 95%

Molecular weight: 718 g/mol

Ref: 3D-BBA66294