CAS 2668-66-8

Medrysone

Description:

Medrysone is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, primarily used in ophthalmic formulations. It is characterized by its ability to reduce inflammation and is often employed in the treatment of various eye conditions, such as allergic conjunctivitis and post-operative inflammation. Medrysone is known for its moderate potency compared to other corticosteroids, making it suitable for conditions where a less aggressive treatment is warranted. The compound exhibits a relatively low systemic absorption when applied topically, which minimizes potential side effects associated with systemic corticosteroid use. Its chemical structure includes a steroid nucleus, which is typical of corticosteroids, contributing to its mechanism of action by modulating gene expression and inhibiting the release of inflammatory mediators. Medrysone is typically formulated as an ophthalmic solution or suspension, and its efficacy is enhanced by its ability to penetrate ocular tissues. As with all corticosteroids, prolonged use may lead to potential side effects, including increased intraocular pressure and cataract formation, necessitating careful monitoring during treatment.

Formula: C₂₂H₃₂O₃

InChI: InChI=1S/C22H32O3/c1-12-9-15-17-6-5-16(13(2)23)22(17,4)11-19(25)20(15)21(3)8-7-14(24)10-18(12)21/h10,12,15-17,19-20,25H,5-9,11H2,1-4H3/t12-,15-,16+,17-,19-,20+,21-,22+/m0/s1

InChI key: InChIKey=GZENKSODFLBBHQ-ILSZZQPISA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@@H]3O)[C@@H](C(C)=O)CC4)[H])(C[C@H](C)C1=CC(=O)CC2)[H])[H]

Synonyms:

• (6α,11β)-11-Hydroxy-6-methylpregn-4-ene-3,20-dione
• 11β-Hydroxy-6α-methylpregn-4-ene-3,20-dione
• 11β-Hydroxy-6α-methylprogesterone
• 11β-Hydroxylmedroxyprogesterone
• 6α-Methyl-Δ4-pregnene-11β-hydroxy-3,20-dione
• 6α-Methyl-Δ⁴_-pregnene-11β-hydroxy-3,20-dione
• HMS
• Hydroxymesterone
• Medrifar
• Medrisona
• Medrocort
• Medryson
• Medrysone
• Nsc 63278
• Ophtocortin
• Pregn-4-ene-3,20-dione, 11β-hydroxy-6α-methyl-
• Spectamedryn
• U 8471
• Visudrisone

Medrysone

CAS: 2668-66-8

Medrysone is a synthetic glucocorticoid for topical use with anti-inflammatory and anti-allergic effects, altering gene expression to reduce inflammation.

Formula: C₂₂H₃₂O₃

Purity: 97.72% - 99.91%

Color and Shape: Solid

Molecular weight: 344.49

Ref: TM-T0977

6α-methyl-11β-hydroxy Progesterone

CAS: 2668-66-8

Formula: C₂₂H₃₂O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 344.4877

Ref: IN-DA00BE2E

Medrysone

CAS: 2668-66-8

Medrysone

Purity: ≥95%

Molecular weight: 344.49g/mol

Ref: 54-BUP16439

Medrysone

Controlled Product

CAS: 2668-66-8

Applications Medrysone is a corticosteroid that is seen to increase intraocular pressure.
References Cantrill, H. et al.: Am. J. Opthalmol., 79, 1012 (1975); Mindel, J. et al.: arch. Opth., 98, 1577 (1980);

Formula: C₂₂H₃₂O₃

Color and Shape: Neat

Molecular weight: 344.49

Ref: TR-M203800