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CAS 26718-69-4

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  • 2'-Deoxy-N7-methylguanosine
    Biosynth
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    2'-Deoxy-N7-methylguanosine

    CAS:
    <p>2'-Deoxy-N7-methylguanosine is a hydrogenolysis product of guanosine. It can be synthesized in four steps from glycosyl chloride, glycosylamine, and methyl iodide. The catalytic hydrogenolysis of 2'-deoxy-N7-methylguanosine with Raney Ni gives the corresponding 6-amino derivative. Hydrolysis of this amino group converts it to a nucleoside. This nucleoside has been shown to hydrolyze with half-life of about 1 hour at pH 8.5 and 37°C. The hydrolysis of purines by 2'-deoxy-N7-methylguanosine is inhibited by adenosine analogues like 2',3'-dideoxyadenosine and 3',4'-dideoxyadenosine.</p>
    Formula:C11H17N5O4
    Purity:Min. 95%
    Molecular weight:283.28 g/mol

    Ref: 3D-ND170198

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