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CAS 26763-19-9

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Polyadenylic acid potassium salt

Description:
Polyadenylic acid potassium salt, commonly referred to as poly(A)K, is a synthetic polynucleotide that consists of a chain of adenine nucleotides linked by phosphodiester bonds, with potassium ions associated with the polymer. This substance is typically used in molecular biology and biochemistry as a component in various assays and experiments, particularly in the study of RNA and gene expression. Poly(A)K is known for its role in stabilizing mRNA molecules and facilitating their translation, making it crucial in the processes of protein synthesis. The potassium salt form enhances its solubility in aqueous solutions, which is beneficial for laboratory applications. Polyadenylic acid is also involved in the regulation of gene expression and can serve as a model for studying RNA interactions. Its characteristics include high molecular weight, the ability to form secondary structures, and reactivity with various enzymes, such as poly(A) polymerases. Overall, polyadenylic acid potassium salt is an important tool in the field of molecular biology, particularly in studies related to RNA functionality and stability.
Formula:(C10H14N5O7P)x·xK
InChI:InChI=1S/C10H14N5O7P.K/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);/t4-,6-,7-,10-;/m1./s1
InChI key:InChIKey=LZQXPZHDEAFWBQ-MCDZGGTQSA-N
SMILES:O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(=O)(O)O)[C@H]1O.[K]
Synonyms:
  • 5′-Adenylic acid, homopolymer, potassium salt
  • 5′-Adenylic acid, polymers, potassium salt
  • PolyA potassium salt
  • Polyadenylic acid potassium salt
  • Poly-5′-adenylic acid potassium salt
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