CAS 26780-50-7: Poly-(DL)-lactide-co-glycolide

Description: Poly-(DL)-lactide-co-glycolide (PLGA) is a biodegradable copolymer derived from lactic acid and glycolic acid, commonly used in biomedical applications such as drug delivery systems and tissue engineering. Its chemical structure consists of repeating units of lactic acid and glycolic acid, which can be varied in ratio to tailor the polymer's properties. PLGA is characterized by its biocompatibility, biodegradability, and ability to form microspheres or films, making it suitable for controlled release formulations. The degradation rate of PLGA can be adjusted by altering the lactide-to-glycolide ratio, influencing its mechanical properties and release kinetics. Additionally, PLGA is soluble in organic solvents like chloroform and dichloromethane, but insoluble in water, which is advantageous for various formulation techniques. Its applications extend beyond pharmaceuticals to include sutures, scaffolds for tissue regeneration, and other medical devices. Overall, PLGA is a versatile polymer that plays a significant role in advancing drug delivery and regenerative medicine.

Formula: (C₆H₈O₄·C₄H₄O₄)x

InChI: InChI=1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI key: InChIKey=LCSKNASZPVZHEG-UHFFFAOYSA-N

SMILES: O=C1OCC(=O)OC1.O=C1OC(C(=O)OC1C)C

Synonyms:

• 5050Dl2A
• Atrigel
• Medisorb
• OsteoScaf
• Poly(D,L-lactide-co-glycolide)
• Poly(DL-lactide-co-glycolide)
• Poly(glycolide-co-lactide)
• Poly(glycolide-lactide)
• Poly(lactide-co-glycolide)
• Poly(lactide-glycolide)
• Poly[(rac-lactide)-co-glycolide]
• Polygalactin
• Polyglactin
• Vicryl
• Glycolide-lactide polymer
• RESOMER RG 503 H
• 1,4-dioxane-2,5-dione - 3,6-dimethyl-1,4-dioxane-2,5-dione (1:1)
• 1,4-Dioxane-2,5-dione, polymer with 3,6-dimethyl-1,4-dioxane-2,5-dione
• p-Dioxane-2,5-dione, polyester with 3,6-dimethyl-p-dioxane-2,5-dione
• 1,4-Dioxane-2,5-dione, 3,6-dimethyl-, polymer with 1,4-dioxane-2,5-dione
• p-Dioxane-2,5-dione, 3,6-dimethyl-, polyester with p-dioxane-2,5-dione

POLY(D,L-LACTIDE-CO-GLYCOLIDE)

CAS: 26780-50-7

• Formula: C₉H₁₈O₄
• Color and Shape: Solid
• Molecular weight: 190.23682000000005

Poly(Dl-Lactide-Glycolide)

CAS: 26780-50-7

Poly(Dl-Lactide-Glycolide)

CAS: 26780-50-7

Poly(Dl-Lactide-Glycolide)

CAS: 26780-50-7

Poly(DL-lactide-co-glycolide), 50:50 lactide glycolide, M.N. 5,000 to 10,000 Da

CAS: 26780-50-7

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: (C₃H₄O₂)x(C₂H₂O₂)y
• Color and Shape: White to almost white

Poly-(DL)-lactide-co-glycolide

CAS: 26780-50-7

• Formula: C₈H₁₄O₄
• Molecular weight: 174.20

Poly(D,L-lactide-co-glycolide), lactide: glycolide (85:15), average MW 50000 to 75000

CAS: 26780-50-7

Lactide: glycolide (85:15); Average MW 50,000 to 75,000

• Purity: 10 To 20%

Poly(D,L-lactide-co-glycolide);lactide:glycolide (50:50), MW 54000-69000Da

CAS: 26780-50-7

Lactide: glycolide (50:50); Ester terminated; Average MW 54,000 to 69,000

• Formula: (C₆H₈O₄·C₄H₄O₄)x
• Purity: Min. 95%
• Color and Shape: Powder

Poly(D,L-lactide-co-glycolide - lactide:glycolide (50:50), average MW 7000-17000Da

CAS: 26780-50-7

Lactide: glycolide (50:50); Average MW 7,000 to 15,000

• Purity: Min. 95%
• Color and Shape: Powder

Poly(D,L-lactide-co-glycolide), lactide: glycolide (50:50), average MW 10000 to 15000

CAS: 26780-50-7

Lactide: glycolide (50:50); Average MW 10,000 to 15,000

• Formula: (C₆H₈O₄•C₄H₄O₄)x
• Purity: Min. 95%

Poly(D,L-lactide-co-glycolide) - lactide: glycolide (75:25), average MW 50000 to 75000

CAS: 26780-50-7

Lactide: glycolide (75:25); Average MW 50,000 to 75,000

• Formula: C₃H₄O₂xC₂H₂O₂y
• Purity: Min. 95%
• Color and Shape: White Powder

Poly(D,L-lactide-co-glycolide) - lactide: glycolide (75:25), average MW 10000 to 15000

CAS: 26780-50-7

Lactide: glycolide (75:25); Average MW 10,000 to 15,000

• Formula: C₃H₄O₂xC₂H₂O₂y
• Purity: Min. 95%

Poly(D,L-lactide-co-glycolide) - lactide: glycolide (90:10), average MW 10000 to 15000

CAS: 26780-50-7

Lactide: glycolide (90:10); Average MW 10,000 to 15,000

• Formula: C₃H₄O₂xC₂H₂O₂y
• Purity: Min. 95%

Poly(D,L-lactide-co-glycolide) - lactide: glycolide (80:20), average MW 10000 to 15000

CAS: 26780-50-7

Poly(D,L-lactide-co-glycolide) is a biodegradable polymer that is used in the fabrication of surgical meshes. It …

• Formula: C₃H₄O₂xC₂H₂O₂y
• Purity: Min. 95%