Retro-indolicidin is a synthetic antimicrobial peptide derived from the naturally occurring indolicidin, which is known for its potent antibacterial properties. This compound exhibits a unique structure characterized by a high proportion of aromatic amino acids, contributing to its ability to disrupt bacterial membranes. Retro-indolicidin is particularly effective against a range of Gram-positive and Gram-negative bacteria, making it a subject of interest in the development of new antimicrobial agents, especially in the face of rising antibiotic resistance. Its mechanism of action typically involves the formation of pores in bacterial membranes, leading to cell lysis. Additionally, retro-indolicidin has been studied for its potential applications in immunology and cancer therapy due to its ability to modulate immune responses. The stability and efficacy of this peptide can be influenced by factors such as pH and ionic strength, which are critical for its therapeutic applications. Overall, retro-indolicidin represents a promising avenue for research in antimicrobial drug development.

Retro-indolicidin

267890-59-5: Retro-indolicidin is a synthetic antimicrobial peptide derived from the naturally occurring indolicidin, which is known for its potent antibacterial properties. This compound exhibits a unique structure characterized by a high proportion of aromatic amino acids, contributing to its ability to disrupt bacterial membranes. Retro-indolicidin is particularly effective against a range of Gram-positive and Gram-negative bacteria, making it a subject of interest in the development of new antimicrobial agents, especially in the face of rising antibiotic resistance. Its mechanism of action typically involves the formation of pores in bacterial membranes, leading to cell lysis. Additionally, retro-indolicidin has been studied for its potential applications in immunology and cancer therapy due to its ability to modulate immune responses. The stability and efficacy of this peptide can be influenced by factors such as pH and ionic strength, which are critical for its therapeutic applications. Overall, retro-indolicidin represents a promising avenue for research in antimicrobial drug development.

<p>Retro-indolicidin, a synthetic analog of the cathelicidin-derived antimicrobial peptide-amide indolicidin, comprises a reversed 13-amino acid sequence isolated</p>

CAS 267890-59-5

Retro-indolicidin

Retro-indolicidin

Ref: TM-T80261