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CAS 26833-86-3

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Isoharringtonine

Description:
Isoharringtonine is a chemical compound classified as a natural alkaloid, primarily derived from the plant species *Harrisonia perforata*. It is known for its potential pharmacological properties, particularly in the field of oncology. Isoharringtonine exhibits a complex molecular structure, characterized by a specific arrangement of carbon, hydrogen, nitrogen, and oxygen atoms. The compound has been studied for its ability to inhibit protein synthesis, which may contribute to its anti-cancer effects by disrupting the growth of malignant cells. Additionally, it has shown promise in treating certain types of leukemia and other hematological malignancies. Isoharringtonine is typically administered in a clinical setting, and its efficacy and safety profile are subjects of ongoing research. As with many bioactive compounds, its mechanism of action involves interaction with various cellular pathways, making it a candidate for further investigation in therapeutic applications. However, like all pharmacological agents, it may also have side effects and contraindications that need to be considered in clinical use.
Formula:C28H37NO9
InChI:InChI=1S/C28H37NO9/c1-16(2)6-9-28(33,24(30)25(31)35-4)26(32)38-23-21(34-3)14-27-8-5-10-29(27)11-7-17-12-19-20(37-15-36-19)13-18(17)22(23)27/h12-14,16,22-24,30,33H,5-11,15H2,1-4H3/t22-,23-,24-,27+,28-/m1/s1
InChI key:InChIKey=CAOHZEUEVKYHPF-XWHOPEMDSA-N
SMILES:O(C([C@]([C@@H](C(OC)=O)O)(CCC(C)C)O)=O)[C@H]1[C@@]2([C@@]3(N(CCC=4C2=CC5=C(C4)OCO5)CCC3)C=C1OC)[H]
Synonyms:
  • Isoharringtonine
  • Cephalotaxine, 4-methyl 2,3-dihydroxy-2-(3-methylbutyl)butanedioate (ester), [3(2R,3S)]-
  • Cephalotaxine, 4-methyl (2R,3S)-2,3-dihydroxy-2-(3-methylbutyl)butanedioate (ester)
  • NSC 141634
  • Cephalotaxine, 3-[4-methyl (2R,3S)-2,3-dihydroxy-2-(3-methylbutyl)butanedioate]
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