(4R,7R)-Moxifloxacin is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily effective against a variety of Gram-positive and Gram-negative bacteria, making it useful in treating respiratory tract infections, skin infections, and other bacterial diseases. The compound features a bicyclic structure with a piperazine ring, which contributes to its mechanism of action by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication and transcription. Moxifloxacin exhibits good oral bioavailability and is often administered in tablet form or via intravenous injection. Its pharmacokinetics include a relatively long half-life, allowing for once-daily dosing. Additionally, it has a favorable safety profile, although potential side effects may include gastrointestinal disturbances, central nervous system effects, and, in rare cases, tendon damage. The stereochemistry of (4R,7R)-Moxifloxacin is crucial for its biological activity, as the specific configuration enhances its binding affinity to bacterial targets. Overall, it is a valuable agent in modern antimicrobial therapy.

(4R,7R)-Moxifloxacin

268545-13-7: (4R,7R)-Moxifloxacin is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily effective against a variety of Gram-positive and Gram-negative bacteria, making it useful in treating respiratory tract infections, skin infections, and other bacterial diseases. The compound features a bicyclic structure with a piperazine ring, which contributes to its mechanism of action by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication and transcription. Moxifloxacin exhibits good oral bioavailability and is often administered in tablet form or via intravenous injection. Its pharmacokinetics include a relatively long half-life, allowing for once-daily dosing. Additionally, it has a favorable safety profile, although potential side effects may include gastrointestinal disturbances, central nervous system effects, and, in rare cases, tendon damage. The stereochemistry of (4R,7R)-Moxifloxacin is crucial for its biological activity, as the specific configuration enhances its binding affinity to bacterial targets. Overall, it is a valuable agent in modern antimicrobial therapy.

CAS 268545-13-7

(4R,7R)-Moxifloxacin

Moxifloxacin EP Impurity G (ent-Moxifloxacin)

Ref: 4Z-M-2715

Moxifloxacin EP Impurity G

Ref: ST-EA-CP-M26007