CAS 26864-56-2

Penfluridol

Description:

Penfluridol is an antipsychotic medication primarily used in the treatment of schizophrenia and other psychotic disorders. It belongs to the class of drugs known as butyrophenones, which are characterized by their ability to block dopamine receptors in the brain, thereby helping to alleviate symptoms of psychosis. Penfluridol is notable for its long half-life, allowing for once-weekly dosing, which can enhance patient compliance. The substance is typically administered in oral form and is known for its sedative effects, which can be beneficial in managing agitation associated with psychotic episodes. Its chemical structure includes a fluorinated phenyl group, contributing to its pharmacological properties. As with many antipsychotics, potential side effects may include extrapyramidal symptoms, weight gain, and metabolic changes. It is essential for healthcare providers to monitor patients for these effects and adjust treatment as necessary. Overall, penfluridol represents a significant option in the pharmacotherapy of chronic psychotic conditions.

Formula: C₂₈H₂₇ClF₅NO

InChI: InChI=1S/C28H27ClF5NO/c29-26-12-7-21(18-25(26)28(32,33)34)27(36)13-16-35(17-14-27)15-1-2-24(19-3-8-22(30)9-4-19)20-5-10-23(31)11-6-20/h3-12,18,24,36H,1-2,13-17H2

InChI key: InChIKey=MDLAAYDRRZXJIF-UHFFFAOYSA-N

SMILES: OC1(C2=CC(C(F)(F)F)=C(Cl)C=C2)CCN(CCCC(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)CC1

Synonyms:

• 1-(4,4-Bis(4-fluorophenyl)butyl)-4-hydroxy-4-(3-trifluoromethyl-4-chlorophenyl)piperidine
• 1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol
• 1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol
• 1-[4,4-Bis(p-fluorophenyl)butyl]-4-(4-chloro-a,a,a-trifluoro-m-tolyl)-4-piperidinol
• 248-074-5
• 4-Piperidinol, 1-[4,4-Bis(4-Fluorophenyl)Butyl]-4-[4-Chloro-3-(Trifluoromethyl)Phenyl]-
• 4-Piperidinol, 1-[4,4-bis(p-fluorophenyl)butyl]-4-(4-chloro-α,α,α-trifluoro-m-tolyl)-
• McN-JR 16341
• R 16341
• Semap
• Penfluridol

Penfluridol

CAS: 26864-56-2

Penfluridol (TLP-607) is a highly potent antipsychotic.

Formula: C₂₈H₂₇ClF₅NO

Purity: 98.9% - 99.87%

Color and Shape: Off-White To White Crystalline Powder

Molecular weight: 523.97

Ref: TM-T1105

Penfluridol

CAS: 26864-56-2

Formula: C₂₈H₂₇ClF₅NO

Purity: ≥ 97.0%

Color and Shape: White to off-white powder or crystals

Molecular weight: 523.97

Ref: 7W-GP7950

Penfluridol

CAS: 26864-56-2

Penfluridol

Purity: ≥98%

Molecular weight: 523.97g/mol

Ref: 54-BUP14062

Penfluridol

CAS: 26864-56-2

Formula: C₂₈H₂₇ClF₅NO

Color and Shape: Neat

Molecular weight: 523.97

Ref: 04-C15933000

Penfluridol

CAS: 26864-56-2

Formula: C₂₈H₂₇ClF₅NO

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 523.97

Ref: 3B-P2076

Penfluridol

Controlled Product

CAS: 26864-56-2

Formula: C₂₈H₂₇ClF₅NO

Color and Shape: Neat

Molecular weight: 523.97

Ref: 86-MM3565.00

Penfluridol-d4

CAS: 26864-56-2

Formula: C₂₈H₂₃D₄ClF₅NO

Molecular weight: 528.00

Ref: 4Z-P-373017

Penfluridol

CAS: 26864-56-2

Formula: C₂₈H₂₇ClF₅NO

Molecular weight: 523.97

Ref: 4Z-P-373001

Penfluridol

Controlled Product

CAS: 26864-56-2

Penfluridol is a chemical agent that inhibits the activity of dopamine receptors. It is a selective D2 receptor antagonist and has been shown to reduce locomotor activity in animals. Penfluridol has also been shown to be effective in treating urothelial carcinoma, which is a type of bladder cancer. It binds to the dopamine D2 receptor and blocks the effects of dopamine on cells in the body, preventing them from signaling for movement. Penfluridol has been shown to be an effective treatment for autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It has also been shown to inhibit autophagy, which is an important cellular process that removes damaged cell parts and recycles nutrients necessary for growth.

Formula: C₂₈H₂₇ClF₅NO

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 523.96 g/mol

Ref: 3D-FP37146