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CAS 268731-07-3

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Fmoc-D-1,2,3,4-Tetrahydronorharman-3-carboxylic acid

Description:
Fmoc-D-1,2,3,4-Tetrahydronorharman-3-carboxylic acid is a chemical compound characterized by its structure, which includes a fluorene-derived Fmoc (9-fluorenylmethoxycarbonyl) protecting group and a tetrahydronorharman moiety. This compound is typically used in peptide synthesis and drug development due to its ability to serve as a building block for more complex molecules. The presence of the carboxylic acid functional group allows for further chemical modifications and conjugations, making it versatile in synthetic chemistry. Its tetrahydronorharman structure contributes to its potential biological activity, as compounds in this class are often investigated for their pharmacological properties. The Fmoc group is particularly useful in solid-phase peptide synthesis, as it can be easily removed under mild basic conditions, facilitating the sequential addition of amino acids. Overall, Fmoc-D-1,2,3,4-Tetrahydronorharman-3-carboxylic acid is a valuable compound in the field of medicinal chemistry and peptide research.
Formula:C27H22N2O4
InChI:InChI=1/C27H22N2O4/c30-26(31)25-13-21-20-11-5-6-12-23(20)28-24(21)14-29(25)27(32)33-15-22-18-9-3-1-7-16(18)17-8-2-4-10-19(17)22/h1-12,22,25,28H,13-15H2,(H,30,31)/t25-/m1/s1
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=O)N1Cc2c(C[C@@H]1C(=O)O)c1ccccc1[nH]2
Synonyms:
  • Fmoc-D-Tpi-OH
  • (3R)-2-[(9H-fluoren-9-ylmethoxy)carbonyl]-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid
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