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CAS 268734-29-8

:

Fmoc-(R)-3-amino-4-(2-chloro-phenyl)-butyric acid

Description:
Fmoc-(R)-3-amino-4-(2-chloro-phenyl)-butyric acid is a synthetic amino acid derivative commonly used in peptide synthesis and drug development. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. This compound features a chiral center, indicated by the (R) configuration, which is crucial for biological activity and specificity. The presence of the 2-chlorophenyl group contributes to its hydrophobic character and may influence its interaction with biological targets. The compound is typically solid at room temperature and is soluble in organic solvents, making it suitable for various synthetic applications. Its structure allows for potential incorporation into peptides, enhancing their stability and bioactivity. As with many chemical substances, proper handling and safety precautions are essential due to potential toxicity or reactivity. Overall, Fmoc-(R)-3-amino-4-(2-chloro-phenyl)-butyric acid is a valuable building block in the field of medicinal chemistry and peptide research.
Formula:C25H22ClNO4
InChI:InChI=1/C25H22ClNO4/c26-23-12-6-1-7-16(23)13-17(14-24(28)29)27-25(30)31-15-22-20-10-4-2-8-18(20)19-9-3-5-11-21(19)22/h1-12,17,22H,13-15H2,(H,27,30)(H,28,29)/t17-/m1/s1
SMILES:c1ccc(c(c1)C[C@H](CC(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12)Cl
Synonyms:
  • (3R)-4-(2-chlorophenyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid
  • Fmoc-D-β-HoPhe(2-Cl)-OH
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