CAS 2688-48-4

Homogentisic acid lactone

Description:

Homogentisic acid lactone, with the CAS number 2688-48-4, is a chemical compound that is derived from the metabolism of the amino acids phenylalanine and tyrosine. It is characterized by its structure, which includes a lactone functional group, indicating that it is a cyclic ester formed from the reaction of a hydroxy acid with itself. This compound is typically found in biological systems and is associated with the metabolic pathway of homogentisic acid, which is an intermediate in the degradation of tyrosine. Homogentisic acid lactone is known for its role in certain metabolic disorders, particularly alkaptonuria, where its accumulation can lead to various health issues. The compound is generally soluble in organic solvents and may exhibit varying degrees of stability depending on environmental conditions such as pH and temperature. Its reactivity can be influenced by the presence of functional groups, making it of interest in both biochemical research and potential therapeutic applications.

Formula: C₈H₆O₃

InChI: InChI=1/C8H6O3/c9-6-1-2-7-5(3-6)4-8(10)11-7/h1-3,9H,4H2

InChI key: InChIKey=POUITAHNNRJWMA-UHFFFAOYSA-N

SMILES: O=C1OC=2C(C1)=CC(O)=CC2

Synonyms:

• 2(3H)-Benzofuranone, 5-hydroxy-
• 2,5-Dihydroxyphenylacetic acid lactone
• 2,5-Dihydroxyphenylacetic acid γ-lactone
• 5-Hydroxy-2(3H)-benzofuranone
• 5-Hydroxy-2-coumaranone
• 5-Hydroxy-3H-benzofuran-2-one
• 5-Hydroxybenzofuran-2-One
• 5-hydroxy-1-benzofuran-2(3H)-one
• Acetic acid, (2,5-dihydroxyphenyl)-, γ-lactone
• Homogentisic acid gamma-lactone
• Homogentisic acid lactone
• Homogentisic acid γ-lactone
• Homogentisic acidγ-lactone
• Homogentisic lactone
• NSC 61996
• 2,5-DIHYDROXYPHENYLACETIC ACID GAMMA-LACTONE
• HOMOGENTISIC GAMMA-LACTONE
• 5-Hydroxy-2(3H)-benzofuranone, 97%
• 5-Hydroxy-2,3-dihydrobenzofuran-2-one
• AKOS BBS-00000246
• 2,5-Dihydroxyphenylacetic γ-lactone ,97%
• 5-Hydroxybenzofuran-2(3H)-one, Homogentisic lactone
• 2,3-DIHYDRO-5-HYDROXYBENZOFURAN-2-ONE
• 2,5-DIHYDROXYPHENYLACETIC ACID GAMMA-LACTONE 97%
• 2,5-Dihydroxyphenylacetic acid lactone, Homogentisic lactone
• 5-HYDROXYBENZOFURAN-2(3H)-ONE

Homogentisic Acid γ-Lactone

CAS: 2688-48-4

Formula: C₈H₆O₃

Purity: >98.0%(GC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 150.13

Ref: 3B-H0630

5-Hydroxybenzofuran-2(3H)-one

CAS: 2688-48-4

Formula: C₈H₆O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 150.1314

Ref: IN-DA003MSJ

Homogentisic acid lactone

CAS: 2688-48-4

Homogentisic acid lactone is a fungal metabolite exhibiting antifungal activity, a substrate for determining serum paraoxonase 1 (PON1) activity.

Formula: C₈H₆O₃

Purity: 97.03%

Color and Shape: Solid

Molecular weight: 150.13

Ref: TM-TN8421

Homogentisic acid γ-lactone

CAS: 2688-48-4

Homogentisic acid γ-lactone

Purity: 97%

Molecular weight: 150.13g/mol

Ref: 54-OR938120

Homogentisic acid γ-lactone

CAS: 2688-48-4

Homogentisic acid gamma-lactone is a synthetic compound that is an inhibitor of the enzyme cytochrome P450. It binds to cytochrome P450 in a competitive manner and inhibits the oxidation of other molecules, such as steroids and fatty acids. Homogentisic acid gamma-lactone has been shown to have an inhibitory effect on the growth of Pseudomonas aeruginosa in vitro. This compound is able to suppress the formation of reactive oxygen species by inhibiting the activity of cytochrome P450. Homogentisic acid gamma-lactone also possesses antifungal properties that may be due to its ability to inhibit the synthesis of ergosterol, which is an important component for fungal cell membranes.

Formula: C₈H₆O₃

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 150.13 g/mol

Ref: 3D-FH23845

5-Hydroxybenzofuran-2(3H)-one

CAS: 2688-48-4

Formula: C₈H₆O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 150.133

Ref: 10-F321666

Homogentisic Acid γ-Lactone

Controlled Product

CAS: 2688-48-4

Applications Homogentisic Acid γ-Lactone (cas# 2688-48-4) is a compound useful in organic synthesis.

Formula: C₈H₆O₃

Color and Shape: Neat

Molecular weight: 150.131

Ref: TR-H593410