CAS 269055-15-4: Etravirine

Description:Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used primarily in the treatment of HIV-1 infection. It is characterized by its ability to inhibit the reverse transcriptase enzyme, which is crucial for the replication of the virus. Etravirine is known for its broad activity against various HIV strains, including those resistant to other NNRTIs, making it a valuable option in antiretroviral therapy. The compound has a complex chemical structure, which contributes to its unique pharmacological properties. It is typically administered orally and is often used in combination with other antiretroviral agents to enhance efficacy and reduce the risk of resistance development. Etravirine is metabolized primarily by the liver, involving cytochrome P450 enzymes, which can lead to drug interactions with other medications. Common side effects may include rash, nausea, and fatigue, but it is generally well-tolerated. Overall, Etravirine represents an important advancement in HIV treatment, particularly for patients with treatment-experienced infections.

Formula:C₂₀H₁₅BrN₆O

InChI:InChI=1S/C20H15BrN6O/c1-11-7-14(10-23)8-12(2)17(11)28-19-16(21)18(24)26-20(27-19)25-15-5-3-13(9-22)4-6-15/h3-8H,1-2H3,(H3,24,25,26,27)

InChI key:InChIKey=PYGWGZALEOIKDF-UHFFFAOYSA-N

SMILES:N#CC1=CC=C(C=C1)NC=2N=C(OC=3C(=CC(C#N)=CC3C)C)C(Br)=C(N2)N

Synonyms:
4-((6-Amino-5-Bromo-2-((4-Cyanophenyl)Amino)-4-Pyrimidinyl)Oxy)-3,5-Dimethyl-Benzonitrile
4-(6-Amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yloxy)-3,5-dimethylbenzonitrile
4-({6-Amino-5-Bromo-2-[(4-Cyanophenyl)Amino]Pyrimidin-4-Yl}Oxy)-3,5-Dimethylbenzonitrile
4-({6-Amino-5-brom-2-[(4-cyanphenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzolcarbonitril
4-[[6-Amino-5-Bromo-2-[(4-Cyanophenyl)Amino]-4-Pyrimidinyl]Oxy]-3,5�CDimethylbenzonitrile
4-[[6-Amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile
6-Amino-5-Bromo-4-(4-Cyano-2,6-Dimethylphenoxy)-2-(4-Cyanophenylamino)Pyrimidine
Benzonitrile, 4-((6-amino-5-bromo-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethyl-
Etravirine [INN]
Etravirine [USAN:INN]
See more synonyms
Intelence
R 165335
R165335-Tmc125
Tmc 125
Tmc125
Unii-0C50Hw4Fo1
Etravirine

Found 12 products.

Product data	Purity	Price range	Estimated delivery
Etravirine CRS REF: 41-Y0002455CAS: 269055-15-4	- - -	455.00 €	Mon 24 Mar 25
Etravirine REF: 45-1266824CAS: 269055-15-4	- - -	1,004.00 €	Tue 25 Mar 25
Benzonitrile,4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl- REF: IN-DA00ILM5CAS: 269055-15-4	95%	To inquire	Mon 24 Mar 25
Etravirine REF: 4Z-E-221CAS: 269055-15-4	- - -	To inquire	Tue 25 Mar 25
Etravirine-d6 REF: 4Z-E-222CAS: 269055-15-4	- - -	To inquire	Tue 25 Mar 25
Etravirine REF: 7W-GP8296CAS: 269055-15-4	- - -	To inquire	Tue 25 Mar 25
Etravirine REF: 3B-E1528CAS: 269055-15-4	>95.0%(T)(HPLC)	180.00 €	Thu 27 Mar 25
Etravirine-d4 REF: 4Z-E-223CAS: 269055-15-4	- - -	To inquire	Mon 31 Mar 25
Etravirine REF: TM-T2551CAS: 269055-15-4	97.61% - 99.56%	49.00 €~898.00 €	Mon 31 Mar 25
Etravirine REF: TR-E937000CAS: 269055-15-4	- - -	138.00 €~1,204.00 €	Thu 03 Apr 25
Etravirine - Bio-X ™ REF: 3D-BA164437CAS: 269055-15-4	Min. 95%	145.00 €	Fri 04 Apr 25
Etravirine REF: 3D-FA16346CAS: 269055-15-4	Min. 98 Area-%	162.00 €~1,975.00 €	Fri 04 Apr 25