CAS 269066-08-2

(2S)-4-[[4-[[1-(4,4-dimethyl-2,6-dioxo-cyclohexylidene)-3-methyl-butyl]amino]phenyl]methoxy]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-butanoic acid

Description:

The chemical substance with the name "(2S)-4-[[4-[[1-(4,4-dimethyl-2,6-dioxo-cyclohexylidene)-3-methyl-butyl]amino]phenyl]methoxy]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-butanoic acid" and CAS number "269066-08-2" is a complex organic compound characterized by its multi-functional structure. It features a butanoic acid backbone with various substituents, including an amino group and a methoxy group, which contribute to its potential biological activity. The presence of a fluorenylmethoxycarbonyl (Fmoc) group indicates its use in peptide synthesis and as a protecting group in organic synthesis. The compound's stereochemistry is specified by the (2S) designation, indicating a specific spatial arrangement of atoms that can influence its reactivity and interaction with biological targets. Additionally, the presence of a cyclohexylidene moiety suggests potential hydrophobic interactions, which may enhance its binding affinity in biological systems. Overall, this compound's intricate structure suggests it may have applications in medicinal chemistry, particularly in drug development or as a biochemical probe.

Formula: C₃₉H₄₂N₂O₈

InChI: InChI=1/C39H42N2O8/c1-23(2)17-31(36-33(42)19-39(3,4)20-34(36)43)40-25-15-13-24(14-16-25)21-48-35(44)18-32(37(45)46)41-38(47)49-22-30-28-11-7-5-9-26(28)27-10-6-8-12-29(27)30/h5-16,23,30,32,40H,17-22H2,1-4H3,(H,41,47)(H,45,46)/t32-/m0/s1

SMILES: CC(C)CC(=C1C(=O)CC(C)(C)CC1=O)Nc1ccc(cc1)COC(=O)C[C@@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12

Synonyms:

• Fmoc-Asp(ODmab)-OH

Fmoc-Asp(ODmab)-OH

CAS: 269066-08-2

Dmab can be removed with 2% hydrazine in DMF generating an indazole which allows the UV-spectrophotometrical monitoring of the cleavage. Conroy et al. used this Asp derivative for the solid-phase synthesis of N-linked glycopeptides. As Dmab represents an unhindered p-substituted Z-derivative, Asp(Dmab)-containing peptides are prone to base-catalyzed aspartimide formation.

Formula: C₃₉H₄₂N₂O₈

Purity: 98.44%

Color and Shape: Whitish Powder

Molecular weight: 666.77

Ref: 01-4028316

Fmoc-Asp(ODMAB)-OH

CAS: 269066-08-2

Formula: C₃₉H₄₂N₂O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 666.7594

Ref: IN-DA00BBP6

Fmoc-Asp(ODMAB)-OH

CAS: 269066-08-2

Fmoc-Asp(ODMAB)-OH

Purity: 98%

Molecular weight: 666.76g/mol

Ref: 54-OR1032124

Fmoc-Asp(ODMAB)-OH

CAS: 269066-08-2

Purity: 98%

Molecular weight: 666.29

Ref: 10-F556392