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CAS 269398-78-9

:

Fmoc-(R)-3-amino-4-(4-nitro-phenyl)-butyric acid

Description:
Fmoc-(R)-3-amino-4-(4-nitro-phenyl)-butyric acid is a chemical compound that serves as a building block in peptide synthesis and drug development. It features a 3-amino group, which contributes to its basicity and reactivity, and a 4-(4-nitro-phenyl) substituent that enhances its aromatic character and may influence its biological activity. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group is commonly used in solid-phase peptide synthesis, providing stability to the amino group during the synthesis process while allowing for selective deprotection under mild conditions. This compound is characterized by its relatively high molecular weight and specific functional groups that can participate in various chemical reactions, such as coupling with other amino acids or peptides. Its nitro group can also impart unique electronic properties, potentially affecting the compound's interaction with biological targets. Overall, Fmoc-(R)-3-amino-4-(4-nitro-phenyl)-butyric acid is a versatile intermediate in the field of medicinal chemistry and peptide research.
Formula:C25H22N2O6
InChI:InChI=1/C25H22N2O6/c28-24(29)14-17(13-16-9-11-18(12-10-16)27(31)32)26-25(30)33-15-23-21-7-3-1-5-19(21)20-6-2-4-8-22(20)23/h1-12,17,23H,13-15H2,(H,26,30)(H,28,29)/t17-/m1/s1
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=N[C@H](Cc1ccc(cc1)N(=O)=O)CC(=O)O)O
Synonyms:
  • (3R)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-(4-nitrophenyl)butanoic acid
  • Fmoc-D-β-HoPhe(4-NO2)-OH
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