CAS 269409-70-3

4-Hydroxybenzeneboronic acid pinacol ester

Description:

4-Hydroxybenzeneboronic acid pinacol ester, with the CAS number 269409-70-3, is an organoboron compound characterized by the presence of a boronic acid functional group and a pinacol ester moiety. This compound typically appears as a white to off-white solid and is soluble in organic solvents such as dichloromethane and ethanol, but has limited solubility in water. It is known for its utility in organic synthesis, particularly in cross-coupling reactions, such as Suzuki-Miyaura coupling, which is pivotal in the formation of carbon-carbon bonds. The presence of the hydroxy group enhances its reactivity and makes it a valuable intermediate in the synthesis of various pharmaceuticals and agrochemicals. Additionally, the boronic acid functionality allows for the formation of reversible covalent bonds with diols, which can be exploited in sensor applications and materials science. Care should be taken when handling this compound, as boron-containing compounds can exhibit specific reactivity and toxicity profiles.

Formula: C₁₂H₁₇BO₃

InChI: InChI=1/C12H17BO3/c1-11(2)12(3,4)16-13(15-11)9-5-7-10(14)8-6-9/h5-8,14H,1-4H3

SMILES: CC1(C)C(C)(C)OB(c2ccc(cc2)O)O1

Synonyms:

• 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
• Phenol, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
• 4-Hydroxyphenylboronic acid pinacol ester

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

CAS: 269409-70-3

Formula: C₁₂H₁₇BO₃

Purity: >98.0%(GC)

Color and Shape: White to Gray to Brown powder to crystal

Molecular weight: 220.08

Ref: 3B-T1954

4-Hydroxybenzeneboronic acid pinacol ester, 97%

CAS: 269409-70-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₂H₁₇BO₃

Purity: 97%

Color and Shape: White to pale brown, crystalline powder

Molecular weight: 220.08

Ref: 02-H27836

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, min. 97%

CAS: 269409-70-3

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, min. 97%

Formula: C₁₂H₁₇BO₃

Purity: min. 97%

Color and Shape: pale yellow pwdr.

Molecular weight: 220.08

Ref: 08-05-1044

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

CAS: 269409-70-3

Formula: C₁₂H₁₇BO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 220.0726

Ref: IN-DA003LJR

4-Hydroxybenzeneboronic acid, pinacol ester

CAS: 269409-70-3

4-Hydroxybenzeneboronic acid, pinacol ester

Formula: C₁₂H₁₇BO₃

Purity: 98%

Color and Shape: pale yellow solid

Molecular weight: 220.07257g/mol

Ref: 54-OR11014

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

CAS: 269409-70-3

Formula: C₁₂H₁₇BO₃

Purity: ≥ 98.0%

Color and Shape: Off-white to tan powder or crystals

Molecular weight: 220.07

Ref: 7W-GX8123

4-Hydroxyphenylboronic acid pinacol ester

CAS: 269409-70-3

4-Hydroxyphenylboronic acid pinacol ester is a hydrophilic compound that has been used as a long-acting iron chelator. It has been shown to be active in the treatment of anemic patients with chronic kidney disease. 4-Hydroxyphenylboronic acid pinacol ester has been shown to bind to hepcidin, which is a peptide hormone that regulates iron homeostasis in the body by decreasing its absorption from the gut and increasing its excretion. It also binds to functional groups on proteins and other molecules, which allow for selective targeting of certain tissues or cells. This compound can be activated by light, making it photochromic. The addition of an active oxygen atom enables this molecule to react at a faster rate than most compounds and also creates reactive oxygen species (ROS) in humans when activated.

Formula: C₁₂H₁₇BO₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 220.1 g/mol

Ref: 3D-FH33842

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

CAS: 269409-70-3

Formula: C₁₂H₁₇BO₃

Purity: 97%

Color and Shape: Pale brown powder

Molecular weight: 220.08

Ref: 10-F010837