CAS 269718-83-4

Pardoprunox hydrochloride

Description:

Pardoprunox hydrochloride is a chemical compound that acts as a dopamine receptor agonist, primarily targeting the D2 and D3 subtypes. It is classified as a potential treatment for various neurological disorders, including Parkinson's disease and schizophrenia, due to its ability to modulate dopaminergic activity in the brain. The compound is typically presented as a hydrochloride salt, which enhances its solubility and stability in aqueous solutions. Pardoprunox has been studied for its pharmacological properties, including its effects on motor function and cognitive performance. Its mechanism of action involves stimulating dopamine receptors, which can help alleviate symptoms associated with dopamine deficiency. Additionally, the compound may exhibit a favorable side effect profile compared to traditional dopaminergic therapies, making it a subject of interest in clinical research. As with any pharmacological agent, understanding its pharmacokinetics, potential interactions, and safety profile is crucial for its therapeutic application.

Formula: C₁₂H₁₅N₃O₂·ClH

InChI: InChI=1S/C12H15N3O2.ClH/c1-14-5-7-15(8-6-14)10-4-2-3-9-11(10)17-12(16)13-9;/h2-4H,5-8H2,1H3,(H,13,16);1H

InChI key: InChIKey=NQRIKTDKFHAOKC-UHFFFAOYSA-N

SMILES: O=C1OC2=C(C=CC=C2N1)N3CCN(C)CC3.Cl

Synonyms:

• 2(3H)-Benzoxazolone, 7-(4-methyl-1-piperazinyl)-, hydrochloride (1:1)
• 2(3H)-Benzoxazolone, 7-(4-methyl-1-piperazinyl)-, monohydrochloride
• DU 126891 hydrochloride
• Pardoprunox hydrochloride
• SLV 308 hydrochloride
• Slv-308
• Sme-308

Pardoprunox hydrochloride

CAS: 269718-83-4

Pardoprunox hydrochloride

Purity: ≥98%

Molecular weight: 269.73g/mol

Ref: 54-BUP02191

Pardoprunox hydrochloride

CAS: 269718-83-4

Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1)

Formula: C₁₂H₁₆ClN₃O₂

Purity: 98.95% - 99.13%

Color and Shape: Solid

Molecular weight: 269.73

Ref: TM-T3431

Pardoprunox HCl

CAS: 269718-83-4

Formula: C₁₂H₁₅N₃O₂·HCl

Molecular weight: 233.27 36.46

Ref: 4Z-P-354001

Pardoprunox Hydrochloride

Controlled Product

CAS: 269718-83-4

Applications Pardoprunox Hydrochloride is an antiparkinsonian drug currently under development by Solvay for the treatment of Parkinson's disease.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Glennon, Jeffrey C., et al.: Synapse, 60, 599 (2006); Wolf, William A., et al.: Current Opinion in Investigational Drugs, 4, 878 (2003); Tayarani-Binazir, K., et al.: Exp. Neurol.: 226, 320 (2010)

Formula: C₁₂H₁₅N₃O₂·ClH

Color and Shape: Neat

Molecular weight: 269.727

Ref: TR-P205908