CAS 26974-09-4

4-phenyl-6-(trifluoromethyl)-2-pyrimidinylamine

Description:

4-Phenyl-6-(trifluoromethyl)-2-pyrimidinylamine is a chemical compound characterized by its pyrimidine core, which is a six-membered heterocyclic ring containing two nitrogen atoms at positions 2 and 4. The presence of a phenyl group at the 4-position and a trifluoromethyl group at the 6-position contributes to its unique properties. This compound is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. The trifluoromethyl group enhances its lipophilicity and can influence its biological activity, making it of interest in medicinal chemistry. The amine functional group can participate in hydrogen bonding, which may affect its reactivity and interactions with biological targets. Additionally, the compound may exhibit specific spectral characteristics in techniques such as NMR and IR spectroscopy, allowing for its identification and characterization. Overall, 4-phenyl-6-(trifluoromethyl)-2-pyrimidinylamine is notable for its structural features that may confer unique chemical and biological properties.

Formula: C₁₀BrF₇

InChI: InChI=1/C10BrF7/c11-3-4(12)1-2(5(13)8(3)16)7(15)10(18)9(17)6(1)14

SMILES: c12c(c(c(c(c1F)Br)F)F)c(c(c(c2F)F)F)F

Synonyms:

• 4-Phenyl-6-(Trifluoromethyl)Pyrimidin-2-Amine
• 2-Bromo-1,3,4,5,6,7,8-Heptafluoronaphthalene
• 2-Amino-4-Phenyl-6-(Trifluoromethyl)Pyrimidine

2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine

CAS: 26974-09-4

2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine

Purity: 95%

Color and Shape: Solid

Molecular weight: 239.20g/mol

Ref: 54-PC0914

2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine

CAS: 26974-09-4

Formula: C₁₁H₈F₃N₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 239.201

Ref: 10-F493999

2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine

CAS: 26974-09-4

2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine is a nucleoside analog that acts as a DNA and RNA activator. It is used as a component in antiviral drugs, anticancer drugs, and antiretroviral drugs. This compound is structurally similar to the natural nucleosides adenosine and cytidine. It has been shown to inhibit the growth of various cancer cell lines with IC50 values ranging from 6.5 to 25 nM.

Formula: C₁₁H₈F₃N₃

Purity: Min. 95%

Molecular weight: 239.2 g/mol

Ref: 3D-NA57415