CAS 26993-30-6: Sphingosine-1-phosphate
Description:Sphingosine-1-phosphate (S1P) is a bioactive lipid molecule that plays a crucial role in various physiological processes, including cell proliferation, survival, migration, and immune responses. It is a sphingolipid metabolite derived from sphingosine, which is phosphorylated by sphingosine kinases. S1P is characterized by its ability to act as a signaling molecule, binding to specific G protein-coupled receptors (S1P receptors) that mediate diverse cellular responses. The substance is soluble in organic solvents and exhibits amphipathic properties, allowing it to interact with both hydrophilic and hydrophobic environments. S1P is involved in the regulation of vascular integrity, lymphocyte trafficking, and neuroprotection, making it significant in both health and disease contexts, including cancer and autoimmune disorders. Its concentration is tightly regulated within cells and extracellular spaces, as it can have different effects depending on its localization and the receptors it activates. Overall, Sphingosine-1-phosphate is a vital component of cellular signaling pathways with implications in various biological functions and therapeutic targets.
Formula:C18H38NO5P
InChI:InChI=1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18+/m0/s1
InChI key:InChIKey=DUYSYHSSBDVJSM-KRWOKUGFSA-N
SMILES:O=P(O)(O)OCC(N)C(O)C=CCCCCCCCCCCCCC
- Synonyms:
- (4E)-2-Amino-3-hydroxy-4-octadecen-1-yl dihydrogen phosphate
- (4E)-2-Amino-3-hydroxy-4-octadecen-1-yldihydrogen-phosphat
- (4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
- 4-Octadecene-1,3-diol, 2-amino-, 1-(dihydrogen phosphate), (2S,3R,4E)-
- 4-Octadecene-1,3-diol, 2-amino-, 1-(dihydrogen phosphate), (E)-<span class="text-smallcaps">D</span>-erythro-
- 4-Octadecene-1,3-diol, 2-amino-, 1-(dihydrogen phosphate), [R-[R*,S*-(E)]]-
- <span class="text-smallcaps">D</span>-erythro-Sphingosine-1-phosphate
- C<sub>18</sub>-Sphingosine 1-phosphate
- Dihydrogène phosphate de (4E)-2-amino-3-hydroxy-4-octadécèn-1-yle
- Proteins, S1P
- See more synonyms
- S1P protein
- Sphingosine 1-phosphate
- Sphingosine 1-phosphic acid
- D-erythro-Sphingosine-1-phosphate
- D-erythro-Sphingosine 1-phosphate
- 4-Octadecene-1,3-diol, 2-amino-, 1-(dihydrogen phosphate), (E)-D-erythro-
