CAS 270076-60-3

Pristinamycin

Description:

Pristinamycin is a naturally occurring antibiotic that is derived from the fermentation of the bacterium *Streptomyces pristinaespiralis*. It is primarily used in the treatment of infections caused by Gram-positive bacteria, particularly those resistant to other antibiotics, such as methicillin-resistant *Staphylococcus aureus* (MRSA). Pristinamycin is a mixture of two components, pristinamycin I and pristinamycin II, which work synergistically to inhibit bacterial protein synthesis by binding to the 50S ribosomal subunit. This mechanism of action makes it effective against a range of pathogens, including some strains of streptococci and enterococci. Pristinamycin is typically administered via injection and is known for its favorable pharmacokinetic properties, including good tissue penetration. However, it may cause side effects such as gastrointestinal disturbances and allergic reactions. Due to its specific spectrum of activity and resistance patterns, it is often reserved for use in cases where other antibiotics are ineffective.

Formula: C₄₅H₅₄N₈O₁₀

Synonyms:

• Ostreogrycin
• Pristinamycin
• CS-2277
• CS-2276
• Pristinamycin (9CI, ACI)

Pristinamycin

CAS: 270076-60-3

Pristinamycin, from Streptomyces pristinaespiralis, is a streptogramin antibiotic targeting Gram-positive and resistant bacteria like MRSA.

Formula: C₇₃H₈₉N₁₁O₁₇

Color and Shape: Solid

Molecular weight: 1392.55

Ref: TM-T75278

Pristinamycin

CAS: 270076-60-3

Formula: C₄₅H₅₄N₈O₁₀

Purity: ≥ 98.0%

Color and Shape: White to light yellow powder

Molecular weight: 866.96

Ref: 7W-GK4509

Pristinamycin

CAS: 270076-60-3

Formula: C₄₅H₅₄N₈O₁₀·C₂₈H₃₅N₃O₇

Molecular weight: 866.97 525.60

Ref: 4Z-P-173005

Pristinamycin

CAS: 270076-60-3

Pristinamycin is a streptogramin antibiotic with action on bacterial protein synthesis by binding to the 50S ribosomal subunit and is used for treating staphylococcal and streptococcal infections, including MRSA.

Formula: C₇₃H₈₉N₁₁O₁₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 1,392.55 g/mol

Ref: 3D-AP44830

Pristinamycin (~90%)

Controlled Product

CAS: 270076-60-3

Applications Pristinamycin is a mixture of two components that have a synergistic antibacterial action. The two components are Pristinamycin IIA (V673810) and Pristinamycin IA (P745000).
References Hamilton-Miller, J.: J. Antimicrob. Chemother., 27, 702 (1991)

Formula: C₇₃H₈₉N₁₁O₁₇

Purity: ~90%

Color and Shape: Neat

Molecular weight: 1392.55

Ref: TR-P740000