CAS 27064-96-6

Flunarizine Impurity 5

Description:

Flunarizine Impurity 5, with the CAS number 27064-96-6, is a chemical compound that is recognized as an impurity associated with the pharmaceutical agent flunarizine, which is primarily used as a calcium channel blocker and for the treatment of various neurological disorders. The characteristics of this impurity include its molecular structure, which may differ slightly from the parent compound, potentially affecting its pharmacological properties. Typically, impurities like Flunarizine Impurity 5 are identified through techniques such as chromatography and mass spectrometry. The compound may exhibit different solubility, stability, and reactivity compared to flunarizine, which can influence its behavior in formulations and biological systems. Understanding the characteristics of such impurities is crucial for quality control in pharmaceutical manufacturing, as they can impact the efficacy and safety of the final product. Regulatory guidelines often require the identification and quantification of impurities to ensure compliance with safety standards.

Formula: C₂₆H₂₈ClFN₂

Synonyms:

• Flunarizine EP Impurity B DiHydrochloride
• Flunarizine Impurity 5
• 1-[(RS)-(4-Fluorophenyl)phenylmethyl]-4-[(2E)-3-phenylprop-2-enyl]piperazine Dihydrochloride
• Flunarizine EP Impurity B DiHCl
• Flunarizine Imp.B
• Flunarizine Impurity B
• Flunarizine Impurity 2（Flunarizine EP Impurity B）

Desfluoro Flunarizine Dihydrochloride (1-[(4-Fluorophenyl)-phenylmethyl]-4-(3-phenylprop-2-enyl)piperazine dihydrochloride)

CAS: 27064-96-6

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Formula: C₂₆H₂₇FN₂₂·HCl

Molecular weight: 386.21583

Ref: 45-1A14490

Flunarizine EP Impurity B DiHCl

CAS: 27064-96-6

Formula: C₂₆H₂₇FN₂·2HCl

Color and Shape: White To Off-White Solid

Molecular weight: 386.51 2*36.46

Ref: 4Z-F-084002

Defluoro Flunarizine Dihydrochloride

Controlled Product

CAS: 27064-96-6

Impurity Flumazenil EP Impurity B
Stability Hygroscopic
Applications Defluoro Flunarizine (Flumazenil EP Impurity B) Dihydrochloride, is an impurity of Flunarizine(F455200, Dihydrochloride), which is a calcium channel blocker. Flunarizine is a fluorinated derivative of Cinnarizine and a vasodilator (cerebral and peripheral).
References Desmedt, L.K., et al.: Arzneim.-Forsch., 25, 1408 (1975), Godfraind, T., et al.: Eur. J. Pharmacol., 53, 273 (1979), Nihard, P., et al.: Angiology, 33, 37 (1982), Holmes, B., et al.: Drugs, 27, 6 (1984)

Formula: C₂₆H₂₇FN₂·2ClH

Color and Shape: Neat

Molecular weight: 459.43

Ref: TR-D228700

Defluoro flunarizine dihydrochloride

CAS: 27064-96-6

Defluoro flunarizine dihydrochloride is a research and development drug product that is synthetic. It is an impurity standard, which is used as an analytical reference to determine the purity of a drug product. Defluoro flunarizine dihydrochloride is also an API impurity. The metabolite of this compound has not been fully characterized, but it may be similar to the natural metabolite of Flunarizine. HPLC standards are used for quality control during analysis and synthesis of drugs in the pharmaceutical industry.

Formula: C₂₆H₂₇FN₂

Purity: Min. 95%

Molecular weight: 386.5 g/mol

Ref: 3D-CBA06496

Flunarizine EP Impurity B

CAS: 27064-96-6

Formula: C₂₆H₂₇FN₂(HCl)

Molecular weight: 386.51 : 2(36.46)

Ref: ST-EA-CP-F140010