CAS 27072-45-3

Fluorescein isothiocyanate

Description:

Fluorescein isothiocyanate (FITC) is a fluorescent dye commonly used in biological research and diagnostics. It is characterized by its bright green fluorescence, which is emitted when excited by ultraviolet or blue light. FITC is a derivative of fluorescein, featuring an isothiocyanate functional group that allows it to covalently bind to proteins and other biomolecules, making it a valuable tool for labeling and tracking in various applications, including immunofluorescence and flow cytometry. The compound is soluble in organic solvents and has moderate solubility in water, which facilitates its use in aqueous biological systems. FITC is sensitive to pH and can undergo hydrolysis, leading to a decrease in fluorescence intensity over time. Its stability and reactivity make it essential for conjugation to antibodies and other macromolecules, enabling visualization of cellular structures and processes. However, care must be taken to avoid exposure to light and extreme conditions, as these can affect its fluorescent properties.

Formula: C₂₁H₁₁NO₅S

InChI: InChI=1/C21H11NO5S/c23-12-2-5-16-18(8-12)26-19-9-13(24)3-6-17(19)21(16)15-4-1-11(22-10-28)7-14(15)20(25)27-21/h1-9,23-24H

Synonyms:

• 3',6'-Dihydroxy-5(oder 6)-isothiocyanatospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-on
• 3',6'-Dihydroxy-5(ou 6)-isothiocyanatospiro[isobenzofurane-1(3H),9'-[9H]xanthene]-3-one
• 3',6'-dihidroxi-5(o 6)-isotiocianatoespiro[isobenzofuran-1(3H),9'-[9H]xanteno]-3-ona
• 3',6'-dihydroxy-5(or 6)-isothiocyanatospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
• 3',6'-dihydroxy-5(ou 6)-isothiocyanatospiro[isobenzofuranne-1(3H),9'-[9H]xanthene]-3-one
• 3′,6′-Dihydroxy-5(or 6)-isothiocyanatospiro[isobenzofuran-1(3H),9′-[9H]xanthen]-3-one
• Fitc
• Fluorescein isothiocyanate
• Fluorescein, isothiocyanate (salt)
• Fluorescein, isothiocyanato-
• Fluorescein-5(or 6)-isothiocyanate
• Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-5(or 6)-isothiocyanato-
• Spiro[isobenzofuran-1(3H),9′-[9H]xanthen]-3-one, 3′,6′-dihydroxy-5(or 6)-isothiocyanato-
• 3',6'-Dihydroxy-5-Isothiocyanato-3H-Spiro[2-Benzofuran-1,9'-Xanthen]-3-One
• 3',6'-Dihydroxy-5(Or 6)-Isothiocyanatospiro[Isobenzofuran-1(3H),9'-[9H]Xanthen]-3-One
• Fluorescein-5-Isothiocyanate Isomer I
• 5(6)-Fluorescein Isothiocyanate
• 5-Fluorescein Isothiocyanate, Isomer I
• 2-(6-Hydroxy-3-Oxo-3H-Xanthen-9-Yl)-5-Isothiocyanato-Benzoic Acid
• 5-Lsothiocyanato Fluorescein
• 5-Fluorescein Isothiocyanateisomer
• Fluorescein 5-Isothiocyanate, Isomer 1
• Spectracomp(Tm) Fitc Particles

Fluorescein isothiocyanate

CAS: 27072-45-3

Formula: C₄₂H₂₂N₂O₁₀S₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 778.7615

Ref: IN-DA00BBOB

5(6)-FITC

CAS: 27072-45-3

5(6)-FITC

Purity: ≥98%

Molecular weight: 389.38g/mol

Ref: 54-BUP16569

Fluorescein Isothiocyanate

CAS: 27072-45-3

Fluorescein Isothiocyanate

Purity: 95%

Molecular weight: 389.38g/mol

Ref: 54-OR1013320

5(6)-FITC

CAS: 27072-45-3

5(6)-FITC: an amine-reactive fluorescein used to label antibodies for fluorescence imaging and assays.

Formula: C₂₁H₁₁NO₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 389.38

Ref: TM-T18896

Fluorescein 5(6)-isothiocyanate

CAS: 27072-45-3

Formula: C₂₁H₁₁NO₅S

Purity: ≥ 95.0%

Color and Shape: Yellow or orange powder

Molecular weight: 389.38

Ref: 7W-GT8666

Fluorescein isothiocyanate

CAS: 27072-45-3

Labeling reagent for fluorescent-based applications

Formula: C₂₁H₁₁NO₅S

Purity: Min. 90 Area-%

Color and Shape: Yellow Powder

Molecular weight: 389.38 g/mol

Ref: 3D-FF35415

Fluorescein Isothiocyanate (>85%)

Controlled Product

CAS: 27072-45-3

Stability Moisture Sensitive
Applications Fluorescein Isothiocyanate is a fluorescent reagent with incompletely defined position of the NCS. Fluorescein Isothiocyanate is used in multifunctional uniform nanoparticles composed of a magnetite nanocrystal core and a mesoporous silica shell for magnetic resonance, fluorescence imaging. and drug delivery. Dyes and metabolites.
References Kim, J., et al.: Angew. Chem. Int. Ed., 47, 8438 (2008);

Formula: C₂₁H₁₁NO₅S

Purity: >85%

Color and Shape: Neat

Molecular weight: 389.38

Ref: TR-F485715

Fluorescein Isothiocyanate (mixture of 5- and 6- isomers)

CAS: 27072-45-3

Formula: C₂₁H₁₁NO₅S

Purity: >97.0%(T)(HPLC)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 389.38

Ref: 3B-F0784