CAS 2710221-08-0

Naphtho[2,3-b]furan-2-carboxamide, N-[2-[4-[5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]pentyl]-1-piperidinyl]ethyl]-4,9-dihydro-4,9-dioxo-

Description:

Naphtho[2,3-b]furan-2-carboxamide, with the CAS number 2710221-08-0, is a complex organic compound characterized by its unique structural features, including a naphthofuran core and multiple functional groups. This compound typically exhibits properties such as moderate solubility in organic solvents and potential bioactivity due to its amide and piperidine moieties. The presence of multiple carbonyl groups suggests that it may participate in hydrogen bonding, influencing its reactivity and interactions with biological targets. Its intricate structure may confer specific pharmacological properties, making it of interest in medicinal chemistry. Additionally, the compound's stability and reactivity can be influenced by environmental factors such as pH and temperature. Overall, Naphtho[2,3-b]furan-2-carboxamide represents a class of compounds that may have applications in drug development or as chemical probes in biological research, although further studies would be necessary to fully elucidate its characteristics and potential uses.

Formula: C₃₈H₃₉N₅O₈

Synonyms:

• Naphtho[2,3-b]furan-2-carboxamide, N-[2-[4-[5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]pentyl]-1-piperidinyl]ethyl]-4,9-dihydro-4,9-dioxo-

XD2-149

CAS: 2710221-08-0

XD2-149 is a PROTAC compound designed to target STAT3. It is composed of the PROTAC target protein ligand Napabucasin, the E3 ligase Thalidomide, and the linker NH2-C5-Azacyclohexane-N-Boc. The conjugate of the E3 ligase and linker is Thalidomide-NH-C5-azacyclohexane-N-Boc, with Thalidomideacid serving as the active comparator for the target protein ligand.

Formula: C₃₈H₃₉N₅O₈

Color and Shape: Solid

Molecular weight: 693.75

Ref: TM-T200304