CAS 27115-50-0

p-Methylhippuric acid

Description:

p-Methylhippuric acid, with the CAS number 27115-50-0, is an aromatic compound that belongs to the class of hippuric acids. It is characterized by the presence of a methyl group attached to the para position of the benzene ring of hippuric acid, which is itself a conjugate of benzoic acid and glycine. This compound is typically a white crystalline solid and is soluble in water due to its carboxylic acid functional group. p-Methylhippuric acid is often studied in the context of environmental chemistry and toxicology, as it can serve as a biomarker for exposure to certain aromatic compounds, particularly toluene. Its metabolic pathways in the human body involve conjugation processes, making it relevant in pharmacokinetics and toxicological assessments. Additionally, it may exhibit varying degrees of biological activity, which can be influenced by its structural features. Overall, p-Methylhippuric acid is significant in both industrial applications and health-related studies.

Formula: C₁₀H₁₁NO₃

InChI: InChI=1S/C10H11NO3/c1-7-2-4-8(5-3-7)10(14)11-6-9(12)13/h2-5H,6H2,1H3,(H,11,14)(H,12,13)

InChI key: InChIKey=NRSCPTLHWVWLLH-UHFFFAOYSA-N

SMILES: C(NCC(O)=O)(=O)C1=CC=C(C)C=C1

Synonyms:

• p-Toluric acid
• Glycine, N-(4-methylbenzoyl)-
• Hippuric acid, p-methyl-
• p-Methylhippuric acid
• N-(4-Methylbenzoyl)glycine

N-(p-Toluoyl)glycine

CAS: 27115-50-0

Formula: C₁₀H₁₁NO₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 193.20

Ref: 3B-T0313

Glycine, N-​(4-​methylbenzoyl)​-

CAS: 27115-50-0

Formula: C₁₀H₁₁NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 193.1992

Ref: IN-DA003LS1

4-Methylhippuric acid

CAS: 27115-50-0

4-Methylhippuric acid

Formula: C₁₀H₁₁NO₃

Purity: 98%

Color and Shape: white solid

Molecular weight: 193.20g/mol

Ref: 54-OR925154

4-Methylhippuric acid

Controlled Product

CAS: 27115-50-0

Formula: C₁₀H₁₁NO₃

Color and Shape: Neat

Molecular weight: 193.20

Ref: 04-C15088204

4-Methyl Hippuric Acid

Controlled Product

CAS: 27115-50-0

Applications A substituted hippurate analog as substrate and inhibitor of peptidylglycine α-hydroxylating monooxygenase (PHM).
References Erion, M., et al.: J. Med. Chem., 37, 4430 (1994), Feng, J., et al.: Biochem. J., 350, 521 (2000), Zhang, L., et al.: Cancer Res., 66, 5696 (2006),

Formula: C₁₀H₁₁NO₃

Color and Shape: White To Off-White

Molecular weight: 193.2

Ref: TR-M311975

N-(4-methylbenzoyl)glycine

CAS: 27115-50-0

Formula: C₁₀H₁₁NO₃

Purity: 95%

Molecular weight: 193.202

Ref: 10-F375180

4-Methylhippuric acid

CAS: 27115-50-0

4-Methylhippuric acid is a white crystalline powder that belongs to the class of useful scaffolds and versatile building blocks. It is used as a reaction component in research chemicals, speciality chemicals, and complex compounds. 4-Methylhippuric acid is also used as a reagent in the synthesis of high quality products.

Formula: C₁₀H₁₁NO₃

Purity: Min. 98 Area-%

Molecular weight: 193.20 g/mol

Ref: 3D-M-3784

4-Methyl hippuric acid

CAS: 27115-50-0

4-Methyl hippuric acid is a metabolite of benzoic acid, and is excreted in the urine as an end product of phenylalanine metabolism. The matrix effect is a phenomenon that is observed when chromatographic analysis occurs in the presence of impurities or other substances. It can be minimized by using an optimum concentration of hydrochloric acid to extract the analyte from the sample matrix. 4-Methyl hippuric acid can be detected in urine samples by using a chromatographic method and then quantified by measuring its s-phenylmercapturic acid content. This compound has been used as a marker for determining blood pressure and has also been shown to have antihypertensive effects.

Formula: C₁₀H₁₁NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 193.2 g/mol

Ref: 3D-FM25508