CAS 2712-78-9

Bis(trifluoroacetoxy)iodobenzene

Description:

Bis(trifluoroacetoxy)iodobenzene, with the CAS number 2712-78-9, is an organoiodine compound characterized by its unique structure, which includes an iodine atom bonded to a benzene ring that is further substituted with two trifluoroacetoxy groups. This compound is typically a white to light yellow solid at room temperature and is known for its reactivity, particularly in electrophilic aromatic substitution reactions. The presence of the trifluoroacetoxy groups enhances its electrophilic character, making it a useful reagent in organic synthesis, especially in the formation of carbon-iodine bonds. Additionally, the trifluoroacetoxy groups contribute to the compound's stability and solubility in organic solvents. Bis(trifluoroacetoxy)iodobenzene is often utilized in various chemical transformations, including oxidative processes and as a source of iodine in synthetic pathways. However, due to the presence of iodine and trifluoroacetoxy groups, it should be handled with care, as it may pose health and environmental risks. Proper safety protocols should be followed when working with this compound.

Formula: C₁₀H₅F₆IO₄

InChI: InChI=1S/C10H5F6IO4/c11-9(12,13)7(18)20-17(6-4-2-1-3-5-6)21-8(19)10(14,15)16/h1-5H

InChI key: InChIKey=PEZNEXFPRSOYPL-UHFFFAOYSA-N

SMILES: I(OC(C(F)(F)F)=O)(OC(C(F)(F)F)=O)C1=CC=CC=C1

Synonyms:

• 3-Iodobenzene-1,2-Diyl Bis(Trifluoroacetate)
• Acetic acid, trifluoro-, iodine complex
• BTI
• Benzene, [bis(trifluoroacetoxy)iodo]-
• Bis(Trifluoracetoxy)-Iodobenzene
• Bis(Trifluoroacetoxy) Iodobenzene
• Bis(trifluoroacetato)(phenyl)iodine
• Bis(trifluoroacetato)phenyl iodide
• Bis(trifluoroacetoxy)iodobenzne
• I,I-Bis(trifluoroacetoxy)iodobenzene
• Iodine, phenylbis(2,2,2-trifluoroacetato-κO)-
• Iodine, phenylbis(trifluoroacetato-O)-
• Iodine, phenylbis(trifluoroacetato-κO)-
• Iodobenzene bis(trifluoroacetate)
• Iodobenzene di(trifluoroacetate)
• Iodosobenzene bis(trifluoroacetate)
• Phenylbis(2,2,2-trifluoroacetato-κO)iodine
• Phenylbis(trifluoroacetato-κO)iodine
• Phenylbis(trifluoroacetyloxy)iodine
• Phenyliodine bis(trifluoroacetate)
• Phenyliodine(III) bis(trifluoroacetate)
• Phenyliodoso bis(trifluoroacetate)
• Pifa

[Bis(trifluoroacetoxy)iodo]benzene, 97%

CAS: 2712-78-9

[Bis(trifluoroacetoxy)iodo]benzene acts as a reagent in Pummerer-like reactions. It plays an important role in the direct alfa-hydroxylation of ketones under acidic conditions. It is involved in the cyclization of styryl amines to N-alkyl or N-aryl indoles. It serves as a reagent for the chemoselect

Formula: C₁₀H₅F₆IO₄

Purity: 97%

Color and Shape: Crystals or powder or crystalline powder, White

Molecular weight: 430.04

Ref: 02-L15141

[Bis(trifluoroacetoxy)](phenyl)iodane

CAS: 2712-78-9

[Bis(trifluoroacetoxy)](phenyl)iodane

Formula: C₁₀H₅F₆IO₄

Purity: 97%

Color and Shape: Light red. Solid

Molecular weight: 430.03918

Ref: 54-PC0403

[Bis(trifluoroacetoxy)iodo]benzene

CAS: 2712-78-9

Formula: C₁₀H₅F₆IO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 430.0392

Ref: IN-DA0032I4

Bis-trifluoroacetoxyiodobenzene

CAS: 2712-78-9

Formula: C₁₀H₅F₆IO₄

Purity: ≥ 97.0%

Color and Shape: White to off-white or pale yellow crystalline powder

Molecular weight: 430.04

Ref: 7W-GK8116

(Bis(trifluoroacetoxy)iodo)benzene

CAS: 2712-78-9

(Bis(trifluoroacetoxy)iodo)benzene

Formula: C₁₀H₅F₆IO₄

Purity: 97%

Molecular weight: 430.04

Ref: IN-DG32981

[Bis(trifluoroacetoxy)iodo]benzene

CAS: 2712-78-9

Bis(trifluoroacetoxy)iodobenzene is a reactive, radiating, profile, planar molecule with a frequency of low energy. It has been shown to react in acid analysis and the carbonyl group. The reaction mechanism involves the generation of an intermediate that reacts with oxygen to produce the desired product. The impedance is high at resonance frequencies.

Formula: C₁₀H₅F₆IO₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 430.04 g/mol

Ref: 3D-FB49107

[Bis(trifluoroacetoxy)iodo]benzene

CAS: 2712-78-9

Formula: C₁₀H₅F₆IO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 430.041

Ref: 10-F009038

[Bis(trifluoroacetoxy)iodo]benzene

Controlled Product

CAS: 2712-78-9

Stability Air and Moisture Sensitive
Applications [Bis(trifluoroacetoxy)iodo]benzene is a reagent that is used in the preparation of XEN907, which is a spiro-oxindole blocker of Nav1.7 for the treatment of pain.
References Chowdhury, S., et al.: Bioorg. Med. Chem. Lett., 12, 3676 (2011);

Formula: C₁₀H₅F₆IO₄

Color and Shape: Neat

Molecular weight: 430.04

Ref: TR-B586600