CAS 27127-79-3: Thevetin B

Description:Thevetin B is a toxic compound primarily derived from the seeds of the Thevetia peruviana plant, commonly known as the yellow oleander. It belongs to the class of cardiac glycosides, which are known for their ability to affect heart function. Thevetin B exhibits a structure that includes a steroid nucleus, which is characteristic of many cardiac glycosides, and it is known to inhibit the Na+/K+ ATPase enzyme, leading to increased intracellular sodium and calcium levels. This mechanism can result in enhanced cardiac contractility but also poses significant risks of toxicity, including arrhythmias and potential fatal outcomes if ingested. Thevetin B is not only of interest in toxicology but also in pharmacology, where its effects on cardiac function are studied. Due to its toxic nature, handling Thevetin B requires caution, and it is not used therapeutically in humans. Its CAS number, 27127-79-3, is a unique identifier that facilitates the tracking and regulation of this compound in scientific literature and databases.

Formula:C₄₂H₆₆O₁₈

InChI:InChI=1S/C42H66O18/c1-18-35(60-38-33(50)31(48)29(46)26(59-38)17-55-37-32(49)30(47)28(45)25(15-43)58-37)36(53-4)34(51)39(56-18)57-21-7-10-40(2)20(14-21)5-6-24-23(40)8-11-41(3)22(9-12-42(24,41)52)19-13-27(44)54-16-19/h13,18,20-26,28-39,43,45-52H,5-12,14-17H2,1-4H3/t18-,20+,21-,22+,23-,24+,25+,26+,28+,29+,30-,31-,32+,33+,34-,35-,36-,37+,38-,39-,40-,41+,42-/m0/s1

InChI key:InChIKey=GZVMBXDQUQRICT-RCGIHWJFSA-N

SMILES:O=C1OCC(=C1)C2CCC3(O)C4CCC5CC(OC6OC(C)C(OC7OC(COC8OC(CO)C(O)C(O)C8O)C(O)C(O)C7O)C(OC)C6O)CCC5(C)C4CCC23C

Synonyms:
(3beta,5beta)-3-{[beta-D-glucopyranosyl-(1-> 6)-beta-D-glucopyranosyl-(1-> 4)-(2xi)-6-deoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl]oxy}-14-hydroxycard-20(22)-enolide
(3β,5β)-3-[(O-β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyl-(1→6)-O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-<smallcap>L</span>-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
Card-20(22)-enolide, 3-[(O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→6)-O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-<smallcap>L</span>-glucopyranosyl)oxy]-14-hydroxy-, (3β,5β)-
Thevetin B
card-20(22)-enolide, 3-[[O-beta-D-glucopyranosyl-(1-> 6)-O-beta-D-glucopyranosyl-(1-> 4)-(2xi)-6-deoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl]oxy]-14-hydroxy-, (3beta,5beta)-
Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-, (3β,5β)-
(3β,5β)-3-[(O-β-D-Glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide

Found 5 products.

Product data	Purity	Price range	Estimated delivery
Thevetin B REF: IN-DA00BHZWCAS: 27127-79-3	97.5%	To inquire	Mon 28 Apr 25
Thevetin B REF: TM-TN5141CAS: 27127-79-3	98%	747.00 €	Tue 29 Apr 25
Thevetin B REF: BP-BP4811CAS: 27127-79-3	95%~99%	To inquire	Tue 29 Apr 25
Thevetin B REF: BP-SBP02923CAS: 27127-79-3	95%~99%	To inquire	Tue 29 Apr 25
Thevetin B REF: 3D-CBA12779CAS: 27127-79-3	Min. 95%	361.00 €~1,863.00 €	Mon 23 Jun 25