CAS 2719-21-3

N-(4-Acetylphenyl)acetamide

Description:

N-(4-Acetylphenyl)acetamide, also known as N-(4-acetylphenyl)ethanamide, is an organic compound characterized by its amide functional group. It features an acetyl group attached to a phenyl ring, which is further connected to an acetamide moiety. This compound typically appears as a white to off-white crystalline solid and is soluble in organic solvents such as ethanol and acetone, but has limited solubility in water due to its hydrophobic aromatic structure. It is often used in organic synthesis and may serve as an intermediate in the production of pharmaceuticals and other chemical compounds. The presence of both acetyl and amide functional groups contributes to its reactivity, making it a valuable building block in various chemical reactions. Additionally, it may exhibit biological activity, which can be of interest in medicinal chemistry. Safety data should be consulted for handling and storage, as with any chemical substance, to ensure proper precautions are taken.

Formula: C₁₀H₁₁NO₂

InChI: InChI=1S/C10H11NO2/c1-7(12)9-3-5-10(6-4-9)11-8(2)13/h3-6H,1-2H3,(H,11,13)

InChI key: InChIKey=WECHHDJTILFYQT-UHFFFAOYSA-N

SMILES: N(C(C)=O)C1=CC=C(C(C)=O)C=C1

Synonyms:

• 4-(Acetylamino)phenyl methyl ketone
• 4-Acetamidoacetophenone
• 4-Acetylacetanilide~N,4-Diacetylaniline
• 4′-(Acetylamino)acetophenone
• 4′-Acetylacetanilide
• Acetamide, N-(4-acetylphenyl)-
• Acetanilide, 4′-acetyl-
• N-(4-acetylphenyl)acetamide
• NSC 39449
• p-Acetamidoacetophenone
• p-Acetylacetanilide

4'-Acetamidoacetophenone

CAS: 2719-21-3

Formula: C₁₀H₁₁NO₂

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 177.20

Ref: 3B-A2821

4'-Acetamidoacetophenone, 98%

CAS: 2719-21-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₁NO₂

Purity: 98%

Color and Shape: White to orange to brown, Crystals or powder or crystalline powder

Molecular weight: 177.20

Ref: 02-L03430

N-(4-acetylphenyl)acetamide

CAS: 2719-21-3

Formula: C₁₀H₁₁NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 177.1998

Ref: IN-DA003KM6

4'-Acetamidoacetophenone

CAS: 2719-21-3

4'-Acetamidoacetophenone

Purity: 98%

Color and Shape: Solid

Molecular weight: 177.20g/mol

Ref: 54-OR4673

N-(4-acetylphenyl)acetamide

CAS: 2719-21-3

Formula: C₁₀H₁₁NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 177.203

Ref: 10-F358438

4-Acetylacetanilide

CAS: 2719-21-3

4-Acetylacetanilide is a pyrazoline that can be used as an inhibitor of the enzyme acetylcholinesterase. It has shown high specificity and inhibition concentration values for this enzyme, with a KI of 1.5 μM. 4-Acetylacetanilide also has been found to have a linear relationship with the logarithm of the concentration of inhibitor and with the logarithm of the rate constant for hydrolysis. The model used to predict its inhibitory effect on acetylcholinesterase is based on its active site residues, which are predicted to be H-bond acceptors in intramolecular hydrogen bonds with the substrate's hydroxyl group. This model predicts that 4-acetylacetanilide will bind to acetylcholinesterase in a similar way as physostigmine, a drug that is known to inhibit this enzyme by binding at its active site

Formula: C₁₀H₁₁NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 177.2 g/mol

Ref: 3D-FA67769